Skip to main content
Log in

HL-A bei Lebererkrankungen

HL-A in liver diseases

  • Kurze Wissenschaftliche Mitteilungen
  • Published:
Klinische Wochenschrift Aims and scope Submit manuscript

Summary

Patients treated or controlled at the Second Medical University Clinic and Outpatientclinic Mainz for acute hepatitis (AH), chronic persistent hepatitis (CPH), autoimmune chronic aggressive hepatitis (CAH), liver cirrhosis (CI). or liver diseases due to metabolic disorders (MLK) as well as normal controls were typed for HL-A by the NIH standard test. HL-A 1 and 8 were found to be associated with autoimmune hepatitis (p<0.01).

Zusammenfassung

Patienten mit akuter Hepatitis (AH), chronisch persistierender Hepatitis (CPH), autoimmuner chronisch aggressiver Hepatitis (CAH), Lebercirrhose (CI), metabolisch bedingten Leberkrankheiten (MLK) die in der II. Medizinischen Universitätsklinik und Poliklinik behandelt oder kontrolliert werden, und normale Kontrollpersonen wurden nach der NIH-Standardmethode HL-A typisiert. Bei der chronisch aggressiven Hepatitis wurden HL-A 1 und 8 statistisch signifikant häufiger gefunden (p<0,01).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Bertrams, J., Reis, H. E., Kuwert, E., Selmair, H.: Australia-Antigen. HL-A-Antigene und Lymphocyten-Autoantikörper bei chronisch aggressiver und chronisch persistierender Hepatitis Verh. dtsch. Gesell. inn. Med. im Druck (1973)

  2. Engelfriet, P.: Persönliche Mitteilung

  3. Groote, J. de, Demset, V., Gedigk, P., Korb., G., Popper, H, Poulson, H., Scheuer, P. J., Schmid M., Thaler, H., Uehlinger, E. Weppler, W.: A classification of chronic hepatitis. Lancet1968II, 626–628

  4. Grumet, F. C., Coukell, A., Bodmer, J. G., Bodmer, W. F., McDevitt, H. O.: Histocompatibility (HL-A) antigens associated with systemic Lupus erythematosus. A possible genetic predisposition to disease. New Engl. J. Med.285, 193 (1971)

    PubMed  Google Scholar 

  5. Mackay, J. R., Morris, P. J.: Association of autoimmune active chronic hepatitis with HL-A 1, 8. Lancet1972 II, 793–795

  6. McDevitt, H. O., Bodmer, W. F.: Histocompatibility antigen, immune responsiveness and susceptibility to disease. Amer. J. Med.52, 1 (1972)

    Article  PubMed  Google Scholar 

  7. Mittal, K. K., Mickey, M. R., Singal, D. P., Terasaki, P. I.: Serotyping for homotransplantation. XVIII. Refinement of microdroplet lymphocyte cytotoxicity test. Transplantation6, 913 (1968)

    PubMed  Google Scholar 

  8. Stokes, P. J., Asquith, P., Holmes, G. K. T., Mackintosh, P., Cooke, W. T.: Histocompatibility antigens associated with adult coeliac disease. Lancet1972 II, 162

  9. Thorsby, E., Engeset, A., Lie, S. O.: HL-A antigens and susceptibility to diseases. A study of patients with acute lymphoblastic leukaemia, Hodgkin's disease, and childhood asthma. Tissue Antigens. Vol.1, 147–152 (1971)

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Freudenberg, J., Erdmann, K., Meyer zum Büschenfelde, K.H. et al. HL-A bei Lebererkrankungen. Klin Wochenschr 51, 1075–1076 (1973). https://doi.org/10.1007/BF01468323

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01468323

Key words

Schlüsselwörter

Navigation