Summary
An inerease of dialysate magnesium concentration from 1.5 mval/l to 2.5 mval/l did not reduce significantly i PTH levels in haemodialysed patients, dialysed against 3.5 mEq Ca/l in the dialysate. Thus, when sufficiently high Ca concentrations in the dialysate are used, no further reduction of serum PTH levels is seen by elevating Mg in dialysate.
Zusammenfassung
Die Erhöhung der Dialysat-Magnesium-Konzentration von 1,5 mval/l auf 2,5 mval/l bei Verwendung einer Dialysat-Calcium-Konzentration von 3,5 mval/l führte zu keiner signifikanten Reduktion der radioimmunologisch gemessenen Serum-Parathormonspiegel. Bei ausreichend hohen Dialysat-Calcium-Konzentrationen bewirkt somit die Erhöhung der Dialysat-Magnesiumspiegel keine weitere meßbare Reduktion der PTH-Ausschüttung.
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Ritz, E., Lenhard, V., Bommer, J. et al. The effect of dialysate magnesium concentration on serum PTH-levels in patients on maintenance haemodialysis. Klin Wochenschr 52, 51–53 (1974). https://doi.org/10.1007/BF01468523
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DOI: https://doi.org/10.1007/BF01468523