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Heparinwirkung auf thrombocytäre Enzyme bei chronischer Urämie

Heparin effect on platelet enzymes in chronic uraemia

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Summary

In patients undergoing maintenance haemodialysis in dependence of creatinine-concentration in plasma an inhibition of the enzymes succinic dehydrogenase and NADH-cytochrom-c-reductase in platelets was observed. The inhibition of enzymes was increasing after the administrastration of heparin.

Zusammenfassung

Bei Patienten mit chronischer Uraemie konnte in Abhängigkeit von der Kreatininkonzentration im Serum eine Hemmung der intrathrombocytären Enzyme Succinatdehydrogenase und NADH-Cytochrom-C-Reduktase beobachtet werden, die noch durch Heparin gesteigert werden konnte.

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Authors and Affiliations

  1. Nephrologische Abteilung des Klinikums Westend der Freien Universität Berlin, Germany

    P. Froese, W. Leipnitz & M. Kessel

Authors
  1. P. Froese
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  2. W. Leipnitz
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  3. M. Kessel
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Froese, P., Leipnitz, W. & Kessel, M. Heparinwirkung auf thrombocytäre Enzyme bei chronischer Urämie. Klin Wochenschr 52, 394–395 (1974). https://doi.org/10.1007/BF01468438

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  • DOI: https://doi.org/10.1007/BF01468438

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