Summary
We have studied N-acetyl-β-d-glucosaminidase and α-d-mannosidase activities in human sera from 35 control subjects, 47 normo- and hyperinsulinemic obese persons, and 12 diabetic patients after a fasting period of 12 h and at 30, 60, 90, and 120 min after an oral glucose overload. The results show a significantly higher activity of these 2 enzymes in obese subjects and diabetic patients, of similar magnitude, especially in those obese persons with a higher grade of obesity. Moreover, the activity of these glycosidases decreases in a similar way in all these 3 groups after the oral glucose overload.
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Abbreviations
- BMI:
-
Body mass index
- NAG:
-
N-acetyl-β-d-glucosaminidase
- α-Man:
-
α-d-mannosidase
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Corral, J., Miralles, J.M., García-Pascual, I.J. et al. Increased serum N-acetyl-β-d-glucosaminidase and α-ddd-mannosidase activities in obese subjects. Clin Investig 70, 880–884 (1992). https://doi.org/10.1007/BF00180432
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DOI: https://doi.org/10.1007/BF00180432