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Super-active enkephalin analogues

Simple tripeptide hydroxyalkylamides exhibit surprisingly high and long-lasting opioid activities

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References

  1. Hughes, J., et al.: Nature258, 577 (1975)

    Google Scholar 

  2. Büscher, H.H., et al.: ibid.261, 423 (1976)

    Google Scholar 

  3. Belluzzi, J.D., et al.: ibid.260, 625 (1976)

    Google Scholar 

  4. Miller, R.J., Cuatrecasas, P.: Naturwissenschaften65, 507 (1978)

    Google Scholar 

  5. Kiso, Y., et al.: Peptide Chemistry 1979, p. 199 (ed. Yonehara, H.). Osaka: Protein Research Foundation 1980

    Google Scholar 

  6. Dupont, A., et al.: Life Sci.25, 907 (1977)

    Google Scholar 

  7. Kiso, Y., et al.: J. Chem. Soc. Chem. Commun.1979, 971

  8. Moritoki. H., et al.: J. Pharm. Pharmacol.33, 54 (1981)

    Google Scholar 

  9. Eddy, N.B., Leimbach, D.: J. Pharmacol. Exp. Ther.107, 385 (1953)

    Google Scholar 

  10. Kiso, Y., et al.: Peptide Chemistry 1980 (ed. Okawa, K.). Osaka: Protein Research Foundation (in press)

  11. Morley, J.S.: Ann. Rev. Pharmacol. Toxicol.20, 81 (1980)

    Google Scholar 

  12. Morgan, B.A., et al.: Proc. Fifth Am. Peptide Symp., p. 111 (eds. Goodman, M., Meienhofer, J.). New York: Wiley 1977

    Google Scholar 

  13. McGregor, W.H., Stein, L., Belluzzi, J.D.: Life Sci.23, 1371 (1978)

    Google Scholar 

  14. Kiso, Y., Ukawa, K., Akita, T.: J. Chem. Soc. Chem. Commun.1980, 101; Kiso, Y., et al.: Chem. Pharm. Bull.28, 673 (1980); Kiso, Y., et al.: Peptide Chemistry 1979, p. 193 (ed. Yonehara, H.). Osaka: Protein Research Foundation 1980

  15. Kosterlitz, H.W., Watt, A.J.: Brit. J. Pharmacol. Chemother.33, 266 (1968)

    Google Scholar 

  16. D'Amour, F.E., Smith, D.L.: J. Pharmacol. Exp. Ther.72, 74 (1941)

    Google Scholar 

  17. Siegmund, E., Cadmus, R., Lu, G.: Proc. Soc. Exp. Biol. Med.95, 729 (1957)

    Google Scholar 

  18. Székely, J.I., et al.: Eur. J. Pharmacol.43, 293 (1977)

    Google Scholar 

  19. Roemer, D., et al.: Nature268, 547 (1977)

    Google Scholar 

  20. Pless, J., et al.: Helv. Chim. Acta62, 398 (1979); Roemer, D., Pless, J.: Life Sci.24, 621 (1979)

    Google Scholar 

  21. Tseng, L., Loh, H.H., Li, C.H.: ibid.23, 2053 (1978)

    Google Scholar 

  22. Fujino, M., et al.: Naturwissenschaften66, 625 (1979)

    Google Scholar 

  23. Nakamura, H., Shimizu, M.: Arch. Int. Pharmacodyn. Ther.221, 105 (1976)

    Google Scholar 

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Kiso, Y., Yamaguchi, M., Akita, T. et al. Super-active enkephalin analogues. Naturwissenschaften 68, 210–212 (1981). https://doi.org/10.1007/BF01047210

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  • DOI: https://doi.org/10.1007/BF01047210

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