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Comparing methods to detect more than one QTL on a chromosome

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Abstract

 The aim of this paper was to compare different methods for testing the presence of one versus multiple QTLs on a same chromosome. We describe different methods that have partially been taken out of the literature. We perform simulations covering different situations to compare the power of these methods for detecting more than one QTL. None of the tests considered appear to be similar; that is, the first-type error depends on the value of the parameters concerning the first QTL. The method starting with a two-QTL model is the most powerful in many situations.

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Authors and Affiliations

  1. Unité de Biométrie et Intelligence Artificielle, Institut National de la Recherche Agronomique (INRA) Centre de recherches de Toulouse, Chemin de Borde Rouge, Auzeville, 31326 Castanet Tolosan, France E-mail: goffinet@toulouse.inra.fr, , , , , , FR

    B. Goffinet & B. Mangin

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  1. B. Goffinet
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  2. B. Mangin
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Received: 15 March 1997 / Accepted: 19 September 1997

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Goffinet, B., Mangin, B. Comparing methods to detect more than one QTL on a chromosome. Theor Appl Genet 96, 628–633 (1998). https://doi.org/10.1007/s001220050781

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  • DOI: https://doi.org/10.1007/s001220050781

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