Conclusions
It seems that the methods described in 1971 have proved to be useful. Advances in other fields have greatly simplified their adoption. The availability of genetically engineered human proteins, together with monoclonal antibodies, suggests that the next few years will see a very large growth in the use of highly specific immunoradiometric assays for a wide variety of polypeptides, many of relevance to research in diabetes. Perhaps we may even finally describe what is really happening to plasma insulin and its related polypeptides during the different stages and in the different types of diabetes. Advances in our understanding of the basic mechanisms of the immune system, together with their role in diabetes, suggest that immunological methods and concepts will be at least as relevant to the subject in the next 25 years.
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Hales, C.N. Immunological techniques in diabetes research: 14 years on. Diabetologia 28, 514–519 (1985). https://doi.org/10.1007/BF00281985
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DOI: https://doi.org/10.1007/BF00281985