Skip to main content
SpringerLink
Log in

Pubertal dependent effects of cadmium on episodic prolactin secretion in male rats

  • SHORT COMMUNICATION
  • Published:
Archives of Toxicology Aims and scope Submit manuscript

Abstract

This work was undertaken to assess if exposure to cadmium related to puberty may affect the episodic pattern of prolactin. Male rats were submitted to cadmium exposure, from day 30 to 60 or from day 60 to 90 of life respectively, at a dose of 50 ppm in the drinking water. Control age-matched rats received cadmium-free water. Prepubertal cadmium administration decreased mean serum prolactin levels and the absolute amplitude of the prolactin pulses. Subchronic exposure to cadmium of adult rats decreased mean serum prolactin levels, the absolute amplitude of the prolactin pulses and their duration, and the mean half-life of the hormone. These results suggest that subchronic cadmium exposure changes the secretory pattern of prolactin in adult male rats in a puberty-dependent way.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Laboratorio de Toxicología, Facultad de Ciencias, Universidad de Vigo, Campus de Orense, 32004-Orense, Spain, , , , , , ES

    A. Lafuente, E. Alvarez-Demanuel & N. Márquez

  2. Dept. Bioquímica, Facultad de Medicina, Universidad Complutense, 28040-Madrid, Spain e-mail: lafuente@uvigo.es Tel.: 34 988 387077, 34 988 387094; Fax: 34 988 38 70 01, , , , , , ES

    A. I. Esquifino

Authors
  1. A. Lafuente
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Alvarez-Demanuel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Márquez
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. I. Esquifino
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 23 July 1998 / Accepted: 5 November 1998

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lafuente, A., Alvarez-Demanuel, E., Márquez, N. et al. Pubertal dependent effects of cadmium on episodic prolactin secretion in male rats. Arch Toxicol 73, 60–63 (1999). https://doi.org/10.1007/s002040050587

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s002040050587

Search

Navigation