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A comparison of plasma and serum levels of two tricyclic antidepressants: Imipramine and desipramine

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Abstract

This study was performed to determine the difference, if any, between serum and plasma levels of the tricyclic antidepressant drugs imipramine and desipramine. Serum and plasma samples were drawn simultaneously from patients taking either of these drugs. Statistical analysis indicated no difference in the drug levels; that is, serum and plasma levels were identical.

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Authors and Affiliations

  1. Department of Pathology, Medical College of Virginia, MCV Station, Box 597, 23298, Richmond, Virginia, USA

    Joseph J. Saady

  2. Department of Psychiatry, Medical College of Virginia, MCV Station, Box 597, 23298, Richmond, Virginia, USA

    Valerie L. Bloom, N. Narasimhachari, Solomon C. Goldberg & Robert O. Friedel

Authors
  1. Joseph J. Saady
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  2. Valerie L. Bloom
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  3. N. Narasimhachari
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  4. Solomon C. Goldberg
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  5. Robert O. Friedel
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Saady, J.J., Bloom, V.L., Narasimhachari, N. et al. A comparison of plasma and serum levels of two tricyclic antidepressants: Imipramine and desipramine. Psychopharmacology 75, 173–174 (1981). https://doi.org/10.1007/BF00432182

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  • DOI: https://doi.org/10.1007/BF00432182

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