Summary
An electronic circuit is described consisting mainly of a current source with an output impedance near 1 GΩ and with a rise time of 16 μs. Combination of this circuit with a fine electropolished platinum microelectrode enables the application of rapid current steps of up to several microamperes to cells of low input resistance under current clamp conditions.
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Koppenhöfer, E., Schramm, M. Intracellular application of strong currents under current clamp conditions. Pflugers Arch. 350, 335–340 (1974). https://doi.org/10.1007/BF00592641
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DOI: https://doi.org/10.1007/BF00592641