Skip to main content
SpringerLink
Log in

The electrostatic molecular potential of yeast tRNAPhe. III. The molecular potential and the steric acessibility associated with the phosphate groups

  • Original Investigations
  • Published:
Theoretica chimica acta Aims and scope Submit manuscript

Abstract

The molecular electrostatic potential of yeast tRNAPhe is calculated at sites bridging the anionic oxygens of each of the 76 phosphate groups of the molecule. A quantitative measure of the steric accessibility of the anionic oxygens of the phosphates toward a spherical cation is presented. Both the resulting potentials and accessibilities are discussed in terms of the molecular and electronic structure of tRNA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Lavery, R., Pullman, A., Pullman, B.: Nucl. Acid Res.8, 1061 (1980)

    Google Scholar 

  2. Lavery, R., de Olivera, M., Pullman, B.: J. Computational Chem., in press (1980)

  3. Sussman, J. L., Holbrook, J. B., Warrant, R. W., Church, G. M., Kim, S-H.: J. Mol. Biol.123, 607 (1978). We have utilized in this work a further refined coordinate system obtained as a personal communication from Dr. S-H. Kim

    Google Scholar 

  4. Clark, B. F. C., in: Companion to biochemistry, A. T. Bull et al. Ed., London: Longmans (1974)

    Google Scholar 

  5. Rich, A., Rajbhandary, U. L.: Ann. Rev. Biochem.45, 805 (1976)

    Google Scholar 

  6. Goddard, J. P.: Prog. Biophys. Molec. Biol.32, 233 (1977)

    Google Scholar 

  7. Pullman, B., Perahia, D., Cauchy, D.: Nucl. Acid Res.6, 3821 (1979)

    Google Scholar 

  8. Goldblum, A., Perahia, D., Pullman, A.: Intern. J. Quantum. Chem.15, 121 (1979)

    Google Scholar 

  9. Pullman, B., Gresh, N., Berthod, H., Pullman, A.: Theoret. Chim. Acta (Berl.)44, 151 (1977)

    Google Scholar 

  10. Lee, B., Richards, F. M.: J. Mol. Biol.55, 379 (1971)

    Google Scholar 

  11. Thiyagarajan, P., Ponnuswamy, P. K.: Biopolymers,18, 2233 (1979)

    Google Scholar 

  12. Pauling, L.: The nature of the chemical bond, 3rd Ed. New York: Cornell University Press (1960)

    Google Scholar 

  13. Webb, J. L. in: Enzymes and metabolic inhibitors. New York: Academic Press (1963)

    Google Scholar 

  14. Holbrook, S. R., Sussman, J. L., Warrant, R. W., Kim, S-H.: J. Mol. Biol.123, 631 (1978)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut de Biologie Physico-Chimique, Laboratoire de Biochimie Théorique, associé au C.N.R.S., 13, rue P. et M. Curie, 75005, Paris, France

    Richard Lavery, Alberte Pullman & Bernard Pullman

Authors
  1. Richard Lavery
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alberte Pullman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Bernard Pullman
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lavery, R., Pullman, A. & Pullman, B. The electrostatic molecular potential of yeast tRNAPhe. III. The molecular potential and the steric acessibility associated with the phosphate groups. Theoret. Chim. Acta 57, 233–243 (1980). https://doi.org/10.1007/BF00554104

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00554104

Key words

Search

Navigation