Abstract
An online hyphenation of capillary electrophoresis (CE) with inductively coupled plasma-mass spectrometry (ICP-MS) is developed, using a homemade nebulizer as the interface. The high resolution power of CE is used for the separation of metal species, whereas ICP-MS is taken for element specific detection with low detection limits. Metal species of standard solutions and real samples are separated and monitored by UV and ICP-MS. After optimization, electropherograms with high resolution were obtained, showing low detection limits around 1 μg/L (e.g. Pt-species) and very high resolution. Typical analysis times were below 22 min. Quality control aspects concerned species stability during the analytical procedure and stability of electrical current during nebulization. A possible interfering suction flow was estimated and found to be negligible.
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Received: 17 April 1996 / Revised: 12 June 1996 / Accepted: 20 June 1996
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Michalke, B., Schramel, P. Coupling of capillary electrophoresis with ICP-MS for speciation investigations. Fresenius J Anal Chem 357, 594–599 (1997). https://doi.org/10.1007/s002160050220
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DOI: https://doi.org/10.1007/s002160050220