Summary
The regional distribution of GABA in the CNS of rabbit (17 regions), rat (14 regions), guinea pig (12 regions) and baboon (11 regions) was determined by sensitive enzymatic and fluorometric assay. In all species studied a high concentration of GABA was found in substantia nigra (8.5–10.1 mmoles/kg) and pallidum (6.5–8.2 mmoles/kg). Fairly high amounts were found in hypothalamus, superior and inferior colliculi, nucleus oculomotorius and dentate nucleus. The GABA concentration in spinal cord (white matter) had the lowest value.
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On leave from Institute of Brain Research, University of Tokyo, Tokyo, Japan.
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Okada, Y., Nitsch-Hassler, C., Kim, J.S. et al. Role of γ-aminobutyric acid (GABA) in the extrapyramidal motor system 1. Regional distribution of GABA in rabbit, rat, guinea pig and baboon CNS. Exp Brain Res 13, 514–518 (1971). https://doi.org/10.1007/BF00234282
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DOI: https://doi.org/10.1007/BF00234282