Skip to main content
Log in

Dual mode of projections from the parietal to the motor cortex in the cat

  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Summary

1. The cortico-cortical projection from area 5 to area 4 γ was studied in anesthetized cats. 2. Intracortical microstimulation of area 5 produced EPSPs in pyramidal tract (PT) cells in area 4 γ. Such EPSPs were analysed in a total of 54 fast PT cells. The rising phase of these EPSPs was often composed of fast and slow components. 3. Fast-rising EPSPs (fast component) were produced predominantly by stimulation within layer III of area 5 while slow-rising EPSPs (slow component) were evoked predominantly by stimulation within layer V of area 5. 4. The amplitudes of the fast and slow components of EPSPs produced during repetitive stimulation within layers III and V of area 5 decreased and increased, respectively, with an increase in the stimulus frequency without any appreciable changes in their latency and time-to-peak. The slow component was much less influenced by membrane hyperpolarization than the fast component. 5. Retrogradely labeled neurons were found not only in layer III but also in layer V of area 5 following HRP injection centered on superficial layers (I–III) of area 4γ. 6. It is suggested that there are two groups of cortico-cortical neurons in layers III and V of area 5, which may make monosynaptic contact with the proximal and distal sites of fast PT cells in area 4γ, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Asanuma H, Rosen I (1973) Spread of mono- and polysynaptic connections within cats motor cortex. Exp Brain Res 16: 507–520

    Google Scholar 

  • Asanuma H, Arnold AP (1975) Noxious effect of excessive currents used for intracortical microstimulation. Brain Res 96: 103–107

    Google Scholar 

  • Asanuma H, Arnold A, Zarzecki P (1976) Further study on the excitation of pyramidal tract cells by intracortical microstimulation. Exp Brain Res 26: 443–461

    Google Scholar 

  • Babb RS, Waters RS, Asanuma H (1984) Corticocortical connections to the motor cortex from the posterior parietal lobe (area 5a, 5b, 7) in the cat demonstrated by the retrograde axonal transport of horseradish peroxidase. Exp Brain Res 54: 476–484

    Google Scholar 

  • Deschênes M (1977) Dual origin of fibers projecting from motor cortex to SI in cat. Brain Res 132: 159–162

    Google Scholar 

  • Hassler R, Muhs-Clement K (1964) Architektonischer Aufbau des sensomotorischen und parietalen Cortex der Katze. J Hirnforsch 6: Heft 6

  • Henneman E, Lüscher H-R, Mathis J (1984) Simultaneously active and inactive synapses of single Ia fibers on cat spinal motoneurons. J Physiol 352: 147–161

    Google Scholar 

  • Hirst GDS, Redman SJ, Wong K (1981) Post-tetanic potentiation and facilitation of synaptic potentials evoked in spinal motoneurons by impulses in group Ia fibres. J Physiol 321: 97–110

    Google Scholar 

  • Honig MG, Collins III VF, Mendell LM (1983) α-motoneuron EPSPs exhibit different frequency sensitivities to single Ia-afferent stimulation. J Neurophysiol 49: 886–901

    Google Scholar 

  • Jankowska E, Padel Y, Tanaka R (1975) The mode of activation of pyramidal tract cells by intracortical stimuli. J Physiol 249: 617–636

    Google Scholar 

  • Jones EG, Coulter JD, Hendry SHC (1978) Intracortical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys. J Comp Neurol 181: 291–348

    Google Scholar 

  • Kang Y, Endo K, Araki T (1985) Frequency-to-voltage conversion in the pyramidal tract neuron: an important role of the inhibitory postsynaptic potential. Neurosci Let 57: 175–180

    Google Scholar 

  • Kawamura K (1973) Cortico-cortical fiber connections of the cat cerebrum. II. The parietal region. Brain Res 51: 23–40

    Google Scholar 

  • Kuno M (1964) Mechanism of facilitation and depression of the excitatory synaptic potential in spinal motoneurones. J Physiol 175: 100–112

    Google Scholar 

  • Landly P, Labelle A, Deschênes M (1980) Intracortical distribution of axonal collaterals of pyramidal tract cells in the cat motor cortex. Brain Res 191: 327–336

    Google Scholar 

  • Lüscher H-R, Ruenzel P, Henneman E (1980) Factors that influence distribution of input fom Ia and group II spindle afferents to pools of motoneurons. Adv Physiol Sci 16: 249–257

    Google Scholar 

  • Mountcastle VB, Lynch JC, Georgopoulos A, Sakata H, Acuna C (1975) Posterior parietal association cortex of the monkey for operations within extrapersonal space. J Neurophysiol 38: 871–908

    Google Scholar 

  • Phillips CG, Porter R (1964) The pyramidal projection to motoneurons of some muscle groups of the baboon's forelimb. In: Eccles JC, Schade JP (eds) Physiology of spinal neurons. Elsevier, Amsterdam (Progress in Brain Research, Vol 12, pp 222–242)

    Google Scholar 

  • Porter R, Hore J (1969) Time course of minimal corticomotoneuronal excitatory postsynaptic potentials in lumber motoneurons of the monkey. J Neurophysiol 32: 443–451

    Google Scholar 

  • Porter R (1970) Early facilitation at corticomotoneuronal synapses. J Physiol 207: 733–745

    Google Scholar 

  • Rall W (1969) Time constants and electronic length of membrane cylinders and neurons. Biophys J 9: 1483–1508

    Google Scholar 

  • Redman SJ (1976) A quantitative approach to the integrative function of dendrites. In: Porter R (ed) Neurophysiol II. University Park, Baltimore (International Review of Physiology, Vol 10, pp 1–36)

  • Rosenthal J, Waller HJ, Amassian VE (1967) An analysis of the activation of motor cortical neurons by surface stimulation. J Neurophysiol 30: 844–858

    Google Scholar 

  • Sakata H, Takaoka Y, Kawarasaki A, Shibutani H (1973) Somatosensory properties of neurons in the superior parietal cortex (area 5) with the rhesus monkey. Brain Res 64: 85–102

    Google Scholar 

  • Sloper JJ, Powell TPS (1979) An experimental electron microscopic study of afferent connections to the primate motor and somatic sensory cortices. Philos Trans R Soc Lond B 285: 199–224

    Google Scholar 

  • Stoney SD Jr, Thompson WD, Asanuma H (1968) Excitation of pyramidal tract neurons by intracortical microstimulation: effective extent of stimulating current. J Neurophysiol 31: 659–669

    Google Scholar 

  • Strick PL, Kim CC (1978) Input to primate motor cortex from parietal cortex (area 5). I. Demonstration of retrograde transport. Brain Res 157: 325–330

    Google Scholar 

  • Takahashi K (1965) Slow and fast groups of pyramidal tract cells and their respective membrane properties. J Neurophysiol 28: 908–924

    Google Scholar 

  • Tsukahara N, Kosaka K (1968) The mode of cerebral excitation of red nucleus neurons. Exp Brain Res 5: 102–117

    Google Scholar 

  • Waters RS, Favarov O, Asanuma H (1982) Pattern of projection and physiological properties of cortico-cortical connections from the posterior bank of the ansate sulcus to the motor cortex, area 4γ, in the cat. Exp Brain Res 48: 335–344

    Google Scholar 

  • Zarzecki P, Shinoda Y, Asanuma H (1978a) Projection from area 3a to the motor cortex by neurons activated from group I muscle afferents. Exp Brain Res 33: 269–282

    Google Scholar 

  • Zarzecki P, Strick PL, Asanuma H (1978b) Input to primate motor cortex from posterior parietal cortex (area 5). II. Identification by antidromic activation. Brain Res 157: 331–335

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kang, Y., Endo, K., Araki, T. et al. Dual mode of projections from the parietal to the motor cortex in the cat. Exp Brain Res 62, 281–292 (1986). https://doi.org/10.1007/BF00238847

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00238847

Key words

Navigation