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New MRI findings in Creutzfeldt-Jakob disease: high signal in the globus pallidus on T 1-weighted images

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

We report a 49-year-old woman with Creutzfeldt-Jakob disease (CJD). In addition to typical high-signal lesions on proton-density and T 2-weighted images there was high signal in the globus pallidus bilaterally on T 1-weighted images. The latter feature has not been described previously and probably due to deposition of prion protein, as found at autopsy.

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Authors and Affiliations

  1. Department of Radiology, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands, Tel.: + 31-43-3 87 69 10, Fax: + 31-43-3 87 69 09, , , , , , NL

    J. A. de Priester & J. T. Wilmink

  2. Department of Neuropathology, University Hospital Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands, , , , , , NL

    G. H. Jansen

  3. Department of Neurology, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands, , , , , , NL

    J. R. de Kruijk

Authors
  1. J. A. de Priester
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  2. G. H. Jansen
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  3. J. R. de Kruijk
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  4. J. T. Wilmink
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Received: 15 July 1998 Accepted: 28 September 1998

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de Priester, J., Jansen, G., de Kruijk, J. et al. New MRI findings in Creutzfeldt-Jakob disease: high signal in the globus pallidus on T 1-weighted images. Neuroradiology 41, 265–268 (1999). https://doi.org/10.1007/s002340050744

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  • DOI: https://doi.org/10.1007/s002340050744

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