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Urolithiasis associated with urogenital tuberculosis

Clinical and mineralogical aspects

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Summary

Of 628 patients with bacteriologicaly or histologicaly proven urogenital tuberculosis (UGT) treated from 1960 to 1985. 126 patients (20.1%) had additional urinary tract infection and 66 patients (10.5%) developed urolithiasis. In these 66 patients a simultaneous urinary tract infection occured in 29 cases (43.9%). Twenty-eight calculi were analyzed by a combined crystal-optical and x-ray-diffraction method. A high incidence of struvite/carbonate apatite calculi (11/28) as well as of calcium phosphate calculi (6/28) was found. The texture of 15 calculi was investigated on thin sections by polarization microscopy and a high concentration of organic material was found in both calcium oxalate and struvite/carbonate apatite calculi probably due to the specific and nonspecific infection with deposition of cell and protein degradation products.

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Lenk, S., Schubert, G., Oesterwitz, H. et al. Urolithiasis associated with urogenital tuberculosis. Urol. Res. 16, 157–159 (1988). https://doi.org/10.1007/BF00256011

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