Skip to main content
Log in

Composition of fluids obtained from human epididymal cysts

  • Original Articles
  • Published:
Urological Research Aims and scope Submit manuscript

Summary

The fluid composition of five epididymal spermatocoeles, one epididymal cyst and a hydrocoele was examined. The fluid obtained from the spermatocoeles was a dilute suspension of mainly immotile spermatozoa. The sperm-free fluid contained less protein, phosphate, glucose, triglyceride and cholesterol than serum but more testosterone and chloride than peripheral blood. It contained no epididymal secretion products. Proteins in the fluid differed from those in serum. From the fluid composition these cysts appeared to be continuous with the rete testis, either dilatations of efferent ducts or Haller's superior aberrant duct (vas aberrans of the rete testis). Fluid from an epididymal cyst containing no spermatozoa was mainly of similar composition. In contrast, hydrocoele fluid resembles blood serum.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Belkien L, Bordt, J, Moeller P, Hano R, Nieschlag E (1985) Estradiol in saliva for monitoring follicular stimulation in an in vitro fertilization program. Fertil Steril 44:322

    Google Scholar 

  2. Blum H, Beier H, Gross H (1987) Improved silver staining of plant proteins, RNA and DNA on polyacrylamide gels. Electrophoresis 8:93

    Google Scholar 

  3. Bustos-Obregón E, Holstein A (1976) The rete testis in man: ultrastructural aspects. Cell Tissue Res 175:1

    Google Scholar 

  4. Chandolia RK, Weinbauer GF, Behre HM, Simoni M, Nieschlag E (1991) Comparative effects of chronic administration of the non-steroidal antiandrogens Flutamide and Casodex on the reproductive system of the adult rat. Acta Endocrinol (Copenh) 105:547

    Google Scholar 

  5. Cooper T (1986) The epididymis, sperm maturation and fertilisation. Springer, Berlin Heidelberg New York

    Google Scholar 

  6. Cooper T (1990) In defense of a function for the human epididymis. Fertil Steril 54:965

    Google Scholar 

  7. Cooper T, Jockenhövel F, Nieschlag E (1991) Variation in seminal parameters from fathers. Hum Reprod 6:859

    Google Scholar 

  8. Dym M (1976) The mammalian rete testis — a morphological study. Anat Rec 186:493

    Google Scholar 

  9. Gerris J, Schoysman R (1984) Tunica vaginalis fluid (TVF): hormonal composition. Assessment of testosterone, 5α-dihydrotestosterone, δ4-androstenedione, dehydroepiandrosteronesulphate, estradiol, LH, FSH and PRL. Acta Eur Fertil 15:205

    Google Scholar 

  10. Griffiths J (1893) Observations on the appendix of the testicle, and on the cysts of the epididymis, the vasa efferentia, and the rete testis. J Anat Physiol 28:107

    Google Scholar 

  11. Guérin J, Czyba J (1987) Hydrolytic enzymes detected in fluid and in spermatozoa from different portions of human epididymis. In: Spera G, De Kretser D (eds) Morphological basis of human reproductive function. Plenum Press, London, p 197

    Google Scholar 

  12. Guérin J, Rollet J, Perrin P, Menezo Y, Orgiazzi A, Czyba J (1981) Enzymes in the seminal plasma from azzospermic men: corelation with the origin of their azoospermia. Fertil Steril 36:368

    Google Scholar 

  13. Hammond G, Ruokinen A, Kontturi M, Koskela E, Vihko R (1977). The simultaneous radioimmunoassay of seven steroids in human spermatic and peripheral venous blood. J Clin Endocrinol Metab 45:16

    Google Scholar 

  14. Henkel R (1990) Untersuchungen zur Proteinsekretion der Blastocyste des Kaninchens (Orytologaus cuniculus L.) während der frühen Gravidität. Inaugrural Dissertation, Philipps-University, Marburg/Lahn

  15. Heukeshoeven J, Dernick R (1986) Neue Ergebnisse zum Mechanismus der Silberfärbung. In: Radola B (ed) Elektrophorese Forum. Technical University, Munich p 22

    Google Scholar 

  16. Hinton B, Setchell B (1981) Micropuncture and microanalytical studies of rhesus monkey and baboon epididymis and the human ductus deferens. Am J Primatol 1:251

    Google Scholar 

  17. Hinton B, Pryor J, Hirsch A, Setchell B (1981) The concentration of some inorganic ions and organic compounds in the luminal fluid of the human ductus deferens. Int J Androl 4:457

    Google Scholar 

  18. Huggins C, Johnson A (1933) Chemical observations on fluids of the seminal tract. I. Inorganic phosphorus, calcium, non-protein nitrogen and glucose content of semen and of seminal vesicle, prostate and spermatocoele fluids in man. Am J Physiol 103:574

    Google Scholar 

  19. Jennings M, Temple-Smith P, Smithwick G, Nauau P, Baker H (1987) Patterns of human epididymal fluid proteins on polyacrylamide gel electrophoresis. Int J Androl 10:441

    Google Scholar 

  20. Junera H, Alfonsi M, Fain-Maurel M, Dadoune J (1988) Characterization of regional proteins in tissues and fluids in the human epididymis. Reprod Nutr Dev 28:1267

    Google Scholar 

  21. Karpe B, Fredricsson B, Svensson J, Ritzén E (1982) Testosterone concentration within the tunica vaginalis of boys and adult men. Int J Androl 5:549

    Google Scholar 

  22. Laemmli U (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage. Nature 227:680

    Google Scholar 

  23. Nistal M, Paniagua R (1984) Congenital anomalies of the testis and the epididymis. In: Testicular and epididymal pathology. Thieme-Stratton, New York, p 72

    Google Scholar 

  24. Rolnick D, Kawanoue S, Szanto P, Buch I (1968) Anatomical incidence of testicular appendages. J Urol 100:755

    Google Scholar 

  25. Saitoh K, Terada T, Hatakeyama S (1990) A morphological study of the efferent ducts of the human epididymis. Int J Androl 13:369

    Google Scholar 

  26. Suominen J, Setchell B (1972) Enzymes and trypsin inhibitors in the rete testis fluid of rams and boars. J Repord Fertil 30:235

    Google Scholar 

  27. Thomas L (ed) (1984) Labor and diagnose, appendix 2. Medizinische Verlagsgesellschaft, Marburg/Lahn

    Google Scholar 

  28. Tomamichel G, Bandhauer K (1986) Seminal carnitine content in obstructive azoospermia. Correlation with the anatomic level of obstruction. J Androl 7:324

    Google Scholar 

  29. Waites G (1977) Fluid secretion: In: Johnson A, Gomes W (eds) The testis. Academic Press, New York, p 91

    Google Scholar 

  30. Waites G, Einer-Jensen N (1974) Collection and analysis of rete testis fluid from macaque monkeys. J Reprod Fertil 41:505

    Google Scholar 

  31. Wakeley C (1943) Cysts of the epididymis, the so-called spermatocoele. Br J Surg 31:165

    Google Scholar 

  32. Wollin M, Marshall F, Fink M, Malhotra R, Diamond D (1988) Aberrant epididymal tissue: a significant clinical entity. J Urol 138:1247

    Google Scholar 

  33. World Health Organization (1987) WHO laboratory manual for the examination of human semen and semen-cervical mucus interaction. Cambridge University Press, Cambridge

    Google Scholar 

  34. Yeung C, Cooper T, Meyer R (1987) Immature rat epididymal epithelial cells grown in static primary monolayer culture on permeable supports. II. Histochemistry and ultrastructure. Cell Tissue Res 256:573

    Google Scholar 

  35. Yeung C, Cooper T, Senge T (1990) Histochemical localization and quantification of α-glucosidase in the epididymis of men and laboratory animals. Biol Repord 42:669

    Google Scholar 

  36. Yeung C, Cooper T, Bergmann M (1991) The organization of tubules in the human caput epididymidis and the ultrastructure of their epithelia. Am J Anat 191:261

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported by funds from the Deutsohe Forschungsgemeinschaft (DFG) Ni 130/11-1 C.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cooper, T.G., Raczek, S., Yeung, C.H. et al. Composition of fluids obtained from human epididymal cysts. Urol. Res. 20, 275–280 (1992). https://doi.org/10.1007/BF00300258

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00300258

Key words

Navigation