Abstract
We report on punctate epiphyseal calcifications (stippled epiphyses) in the fetal alcohol syndrome and present the differential diagnosis of chondrodysplasia punctata. A literature survey shows that epiphyseal calcifications accompanying alcoholic embryopathy are regularly located in the lower limbs and rarely found in the upper extremities.
References
Caffey J (1985) Pediatric X-Ray Diagnosis, 8th edn. Year Book Medical Publishers, Chicago, London, Boca Raton, p 529
Gilbert EF, Opitz M, Spranger JW, Langer LO, Wolfson JJ, Visekul C (1976) Chondrodysplasia punctata-rhizomelic form. Eur J Pediatr 123: 89
Badois C, Lavollay B, Bomsel F (1984) Maladie des épiphyses ponctuées (MEP) associée a une foetopathie éthylique (FE). Ann Radiol 26: 244
Maroteaux P, Lavollay B, Bomsell F, Gautry Ph, Vigneron J, Walbaum R (1984) Chondrodysplasie ponctuée et intoxication alcoolique maternelle. Arch Fr Pediatr 41: 547
Paditz E, Rupprecht E (1985) Alkoholembryopathie mit symptomatischer Chondrodysplasia punctata. Helv Paed Acta 40: 61
Sacrez R, Levy JM, Gigonnet JM, Walter JP, Roth A (1964) Maladie congénitale des épiphyses pointillées. Soc Franc de Paed Strasbourg, Réunion de Strasbourg du 10 Octobre 1964, p 991
Villate VH, Galiana C, Salvador M, Caimari M, Del Valle y JM (1986) Enfermedad de las epifisis punteadas y fetopatia alcohólica. An Esp Pediatr 24: 272
Majewski F (1979) Die Alkoholembryopathie: Fakten und Hypothesen. Adv Int Med Pediatr 43: 1
Spranger JW, Opitz JM, Bidder U (1971) Heterogeneity of Chondrodysplasia Punctata. Humangenet 11: 190
Happle R, Koch H, Lenz W (1980) The CHILD Syndrome. Eur J Pediatr 134: 27
Lawrence JJ, Schlesinger AE, Kozlowski K, Poznanski AK et al. (1989) Unusual radiographic manifestations of chondrodysplasia punctata. Skeletal Radiol 18: 15
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Leicher-Düber, A., Schumacher, R. & Spranger, J. Stippled epiphyses in fetal alcohol syndrome. Pediatr Radiol 20, 369–370 (1990). https://doi.org/10.1007/BF02013185
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02013185