Skip to main content
Log in

Recombinant congenic strains — A new tool for analyzing genetic traits determined by more than one gene

  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Bailar, J. C. and Smith, E. M.: Progress against cancer? N. Engl. J. Med. 314: 1226–1232, 1986

    Google Scholar 

  • Bailey, D. W.: A search for genetic background influences on survival time of skin grafts from mice bearing γ-linked histoincompatibility. Transplantation 3: 531–534, 1965

    Google Scholar 

  • Bailey, D. W.: Recombinant-inbred strains. An aid to identify linkage and function of histocompatibility and other genes. Transplantation 11: 325–327, 1971

    Google Scholar 

  • Bailey, D. W.: Recombinant inbred strains and bilineal congenic strains. In H. L. Foster, J. D. Small, and J. G. Fox (eds.): The Mouse in Biomedical Research, pp. 223–239, Academic Press, New York, 1981

    Google Scholar 

  • Bishop, J. M.: Cellular oncogenes and retroviruses. Annu. Rev. Biochem. 52: 301–354, 1983

    Google Scholar 

  • Breindl, M., Harbers, K., and Jaenisch, R.: Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure. Cell 38: 9–16, 1984

    Google Scholar 

  • Briles, D. E., Benjamin, W. H., Jr., and Posey, B.: Use of recombinant inbred mice to study the genetics of disease resistance. In E. Skamene (ed.): Genetic Control of HostResistance to Infection and Malignancy, pp. 97–99, Alan R. Liss, New York, 1985

    Google Scholar 

  • Briles, D. E., Benjamin, W. H., Jr., Huster, W. J., and Posey, B.: Genetic approaches to the study of disease resistance with special emphasis on the use of recombinant inbred mice. Curr. Top. Microbiol. Immunol. 124: 21–35, 1986

    Google Scholar 

  • Brinster, R. L., Chen, H. Y., Messing, A., van Dyke, T., Levine, A. L., and Palmiter, R. D.: Transgenic mice harboring SV40T antigen develop characteristic tumors. Cell 37: 367–379, 1984

    Google Scholar 

  • Cairns, J.: The treatment of diseases and the war against cancer. Sci. Am. 253: 31–39, 1985

    Google Scholar 

  • Dickie, M. M.: The use of F1 hybrid and backcross generations to reveal new and/or uncommon tumor types. J. Natl. Cancer Inst. 15: 791–799, 1954

    Google Scholar 

  • Falconer, D. S.: Quantitative inheritance. In W. J. Burdette (ed.): Methodology in Mammalian Genetics, pp. 193–216, Holden-Day, San Francisco, 1963

    Google Scholar 

  • Festenstein, H. and Demant, P.: HLA and H-2-Basic Immunogenetics. Edward Arnold, London, 1978

    Google Scholar 

  • Gehring, W. J. and Paro, R.: Isolation of a hybrid plasmid with homologous sequences to a transposing element of Drosophila melanogaster. Cell 19: 897–904, 1980

    Google Scholar 

  • Gilmour, D. G., Collins, W. M., Frederickson, T. L., Urban, W. E., Jr., Ward, P. F., and DiFronzo, N. L.: Genetic interaction between non-MHC T and B-cell alloantigens in response to Rous sarcomas in chickens. Immunogenetics 23: 1–6, 1986

    Google Scholar 

  • Gorer, P. A.: The detection of antigenic differences in mouse erythrocytes by employment of immune sera. Br. J. Exp. Pathol. 17: 42–40, 1936

    Google Scholar 

  • Green, S., Walter, P., Kumar, V., Krust, A., Bornert, J. M., Argos, P., and Chambon, P.: Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A. Nature 320: 134–139, 1986

    Google Scholar 

  • Haldane, J. B. S. and Waddington, C. H.: Inbreeding and linkage. Genetics 16: 357–374, 1931

    Google Scholar 

  • Hanahan, D.: Heritable formation of pancreatic beta-cell tumors in transgenic mice expressing recombinant insulin SV40 oncogenes. Nature 315: 115–122, 1985

    Google Scholar 

  • Heidin, C. H. and Westermark, B.: Growth factors: Mechanism of action and relation to oncogenes. Cell 37: 9–20, 1984

    Google Scholar 

  • Heston, W. E.: Genetics of neoplasia. In W. J. Burdette (ed.): Methodology in Mammalian Genetics, pp. 247–268, San Francisco, Holden-Day, 1963

    Google Scholar 

  • Hutton, J. J.: Biochemical polymorphisms—detection, distribution, chromosomal location, and applications. In H. C. Morse (ed.): Origins of Inbred Mice, pp. 235–254, Academic Press, New York, 1978

    Google Scholar 

  • Jaenisch, R., Jähner, D., Nobis, P., Simon, I., Löhler, J., Harbers, K., and Grotkopp, D.: Chromosomal position and activation of retrovirus genomms inserted into the germ line of mice. Cell 24: 519–529, 1981

    Google Scholar 

  • Jenkins, N. A. and Copeland, N. G.: High frequency germline acquisition of ecotropic MuLV proviruses in SWR/J-RF/J hybrid mice. Cell 43: 811–819, 1985

    Google Scholar 

  • Jenkins, N. A., Copeland, N. G., Taylor, B. A., and Lee, B. K.: Dilute (d) coat color mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome. Nature 293: 370–374, 1981

    Google Scholar 

  • Johnson, N. L. and Kotz, S.: Discrete Distributions, Houghton Mifflin Co., Boston, 1969

    Google Scholar 

  • Klein, G.: The role of gene dosage and genetic transposition in carcinogenesis. Nature 294: 313–318, 1981

    Google Scholar 

  • Klein, J.: Biology of the Mouse Histocompatibility-2 Complex. Springer-Verlag, Berlin, 1975

    Google Scholar 

  • Kouri, R. E., Salerno, R. A., and Whitmire, C. E.: Relationships between aryl hydrocarbon hydroxylase inducibility and sensitivity to chemically induced subcutaneous sarcomas in various strains. J. Natl. Cancer Inst. 50: 363–368, 1973

    Google Scholar 

  • Land, H., Parada, L. F., and Weinberg, R. A.: Cellular oncogenes and multistep carcinogenesis. Science 222: 771–778, 1983

    Google Scholar 

  • Lilly, F.: Fv-2 identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice. J. Natl. Cancer Inst. 45: 163–169, 1970

    Google Scholar 

  • Lilly, F., Boyse, E. A., and Old, L. J.: Genetic basis of susceptibility to viral leukemogenesis. Lancet 2: 1207–1209, 1964

    Google Scholar 

  • Malkinson, A. M., Nesbitt, M., and Skamene, E.: Susceptibility to urethan-induced pulmonary adenomas between A/J and C57BL/J mice: Use of AxB and BxA recombinant inbred lines indicating a three-locus genetic model. J. Natl. Cancer Inst. 75: 971–974, 1985

    Google Scholar 

  • Mather, K.: Historical overview: Quantitative variation and polygenic systems. In J. N. Thompson, Jr., and J. M. Thoday (eds.): Quantitative Genetic Variation, pp. 5–34, Academic Press, New York, 1979

    Google Scholar 

  • Messing, A., Chen, H. Y., Palmiter, R. D., and Brinster, R. L.: Peripheral neuropathias, hepatocellular carcinomas and islet cell adenomas in transgenic mice. Nature 316: 461–463, 1985

    Google Scholar 

  • Möller, G. (ed.): Graft versus host reaction. Immunol. Rev. 80: 1985

  • Murphy, E. D.: Characteristic tumors. In E. L. Green (ed.): Biology of the Laboratory Mouse, pp. 521–570, McGraw-Hill, New York, 1966

    Google Scholar 

  • Myers, R. M., Lerman, L. S., and Maniatis, T.: A general method for saturation mutagenesis of cloned DNA fragments. Science 229: 242–247, 1985

    Google Scholar 

  • Nebert, D. W., Benedict, W. F., and Kouri, R. E.: Aromatic hydrocarbon-produced tumorigenesis and the genetic differences in aryl hydrocarbon hydroxylase induction. In J. Di Paolo and P. Tssó (eds.): World Symposium on Model Systems in Chemical Carcinogenesis, pp. 271–288, Marcel-Dekker, New York, 1974

    Google Scholar 

  • Palmiter, R. D. and Brinster, R. L.: Transgenic mice. Cell 41: 343–345, 1985

    Google Scholar 

  • Roderick, T. H. and Schlager, G.: Multiple factor inheritance. In E. L. Green (ed.): Biology of the Laboratory Mouse, pp. 151–164, McGraw-Hill, New York, 1966

    Google Scholar 

  • Russell, W. L., Hanicker, P. R., Raymer, G. D., Stelle, M. H., Stelzner, K. F., and Thompson, H. M.: Dose-response curve for ethylnitrosourea induced specific locus mutations in mouse spermatogonia. Proc. Natl. Acad. Sci. U.S.A. 79: 3589–3591, 1982

    Google Scholar 

  • Shedlovsky, A., Guenet, J. L., Johnson, L. L., and Dove, W. F.: Induction of recessive mutations in the T/tA-H-2 region of the mouse genome by a point mutagen. Genet. Res., in press, 1986

  • Snell, G. D.: Histocompatibility genes of the mouse. II. Production and analysis of isogenic resistant lines. J. Natl. Cancer Inst. 21: 843–877, 1958

    Google Scholar 

  • Snell, G. D., Dausset, J., and Nathenson, S. G.: Histocompatibility. Academic Press, New York, 1976

    Google Scholar 

  • Stewart, T. A., Pattengale, P. K., and Leder, P.: Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell 38: 627–637, 1984

    Google Scholar 

  • Stiles, C. D.: The biological role of oncogenes-insights from plateletderived growth factor. Cancer Res. 45: 5215–5218, 1985

    Google Scholar 

  • Taylor, B. A.: Recombinant inbred strains: Use in gene mapping. In H. C. Morse (ed.): Origin of Inbred Mice, pp. 423–438, Academic Press, New York, 1978

    Google Scholar 

  • Taylor, B. A.: Recombinant inbred mice: Use in genetic analysis of disease resistance. In E. Skamene, P. A. L. Kougsharn, and M. Landy: Genetic Control of Natural Resistance to Infection and Malignancy, pp. 1–8, Academic Press, New York, 1980

    Google Scholar 

  • Thoday, J. M.: Location of polygenes. Nature 191: 368–370, 1961

    Google Scholar 

  • Tiwari, J. L. and Terasaki, P. I.: HLA and Disease Associations. Springer-Verlag, Berlin, 1985

    Google Scholar 

  • van der Gugten, A. A., Röpcke, G., van Nie, R., and Hilgers, J.: Mouse strain (STS/A) resistant to mammary tumor induction by hypophyseal isographs. Cancer Res. 45: 3448–3453, 1985

    Google Scholar 

  • Wagner, E. F., Covarrubias, L., Stewart, T. A., and Mintz, B.: Prenatal lethalities in mice homozygous for human growth hormone sequence integrated into germ line. Cell 35: 647–655, 1983

    Google Scholar 

  • Weinberger, C., Holenberg, S. M., Rosenfeld, M. G., and Evans, R. M.: Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product. Nature 318: 670–672, 1985

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Démant, P., Hart, A.A.M. Recombinant congenic strains — A new tool for analyzing genetic traits determined by more than one gene. Immunogenetics 24, 416–422 (1986). https://doi.org/10.1007/BF00377961

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00377961

Keywords

Navigation