Abstract
Free and Ca-alginate-immobilized cells of Penicillium raistrickii i 477 were used for 15α-hydroxylation of 13-ethyl-gon-4-en-3,17-dione. The product formation in the presence of β-cyclodetrin, in comparison with reactions carried out in the presence of methanol. Application of β-cyclodextrin led to increasing solubility of the steroid substrate. The fungus was able to utilize β-cyclodextrin as a carbon source.
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Correspondence to: H.-P. Schmauder
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Schlosser, D., Irrgang, S. & Schmauder, H.P. Steroid hydroxylation with free and immobilized cells of Penicillium raistrickii in the presence of β-cyclodextrin. Appl Microbiol Biotechnol 39, 16–20 (1993). https://doi.org/10.1007/BF00166841
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DOI: https://doi.org/10.1007/BF00166841