Abstract
The left-ventricular ejection fraction (LVEF) of 72 patients with aneurysm of the anterior wall was measured by multiple gated blood pool acquisition (MUGA) in the anterior and left anterior oblique (LAO) positions, and by cineangiography (CA) in right anterior oblique (RAO) and LAO projections of 30° and 60°, respectively. The LVEF was overestimated by CA in the LAO projection and by MUGA in the anterior position, but underestimated by CA in the RAO projection (6.1 percentage points) and by MUGA in the LAO position (6.2 percentage points). In 50 patients without aneurysm, no systematical error occurred using MUGA. The underestimation of the LVEF in patients with aneurysm by MUGA in the LAO position is due to differences of photon attenuation in various parts of the cardiac blood pool. This systematical error can be overcome by biplane MUGA.
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Cohn PF, Gorlin R, Douglass FA, Chahine RA, Vokonas PS, Herman MV (1974) Comparison of biplane and single plane left ventriculograms in patients with coronary artery disease. Am J Cardiol 33:1–6
Eilles C, Gerhards, W, Strauss P, Reiners C, Börner W (1982) EKG-getriggerte Emissions-Computer-Tomography der Herzbinneräume — Methoden und klinische Ergebnisse. Der Nuklearmediziner 5:275–283
Karsch KR, Schicha H, Rentrop P, Kreuzer H, Emrich D (1980) Validity of different gated equilibrium blood pool methods for determination of left ventricular ejection fraction. Eur J Nucl Med 5:439–445
Luig H, Bartella R, Carstens B, Domowitz S, Reuter R, Emrich D, Facorro L, Schicha H, Graf M, Karsch KR, Rentrop P, Kreuzer H (1979) Nuklearmedizinische Bestimmung linksventrikulärer Volumenkurven ohne Untergrundkorrektur und ihre Validisierung durch direkten Vergleich mit biplan lävokardiographisch ermittelten Auswurffraktionen. Nucl Med 18:120–124
Schicha H, Emrich D (1983) Nuklearmedizin in der kardiologischen Praxis. Ernst Giebeler Verlag, Darmstadt
Yeh EL, Yeh YS (1981) Theoretical error in radionuclide ejection fraction study due to photon attenuation. Eur J Nucl Med 6:69–71
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Preliminary results were reported at the Symposium of the Working Group on the Use of Isotopes in Cardiology, European Society of Cardiology, Rotterdam, 16th April, 1983
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Schicha, H., Tebbe, U., Neumann, P. et al. Underestimation of left-ventricular ejection fraction by radionuclide ventriculography in patients with aneurysm. Eur J Nucl Med 10, 338–340 (1985). https://doi.org/10.1007/BF00251307
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DOI: https://doi.org/10.1007/BF00251307