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Subchondral vascularisation and osteoarthritis

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Summary

A prospective experiment was carried out in 40 rabbits in which the blood supply to the patella was interrupted for defined periods from 2 weeks to 6 months. With prolonged ischaemia, there were clear changes in the articular cartilage which were comparable with those seen in human osteoarthritis.

Résumé

On a entrepris, sur 40 lapins, un travail expérimental prospectif en interrompant la vascularisation de la rotule durant des périodes allant de 2 semaines à 6 mois. On a constaté qu'une ischémie prolongée entraîne des modifications notables du cartilage articulaire, comparables à celles que l'on observe chez l'homme en cas d'arthrose.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, W-6900, Heidelberg, Federal Republic of Germany

    J. Graf, E. Neusel, U. Freese, H. -G. Simank & F. U. Niethard

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  1. J. Graf
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  2. E. Neusel
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  3. U. Freese
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  4. H. -G. Simank
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  5. F. U. Niethard
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Graf, J., Neusel, E., Freese, U. et al. Subchondral vascularisation and osteoarthritis. International Orthopaedics 16, 113–117 (1992). https://doi.org/10.1007/BF00180198

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