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Abdominal zygomycotic thromboangiitis in a patient with AML and t(1;13;14)

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Abstract

 The case report of a 61 year-old man with AML M2 FAB, t(1; 13; 14) and zygomycotic mesenterial thromboangiitis is presented. Two induction cycles of chemotherapy were administered due to primary drug resistance. They were complicated by pneumonia, colonic pseudo-obstruction and perforation with peritonitis. The patient died on the 40th day of therapy, 4 days after undergoing palliative surgery. Zygomycotic thromboangiitis, which very probably contributed to the intestinal perforation, was confirmed morphologically at necropsy. The novel complex chromosomal translocation t(1; 13; 14) (q31; q32; q24) and the problems connected with the diagnosis of invasive fungal infections are discussed.

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Authors and Affiliations

  1. Department of Hematology, University Hospital, I.P. Pavlova 6, CZ-775 20 Olomouc, Czech Republic, , , , ,

    E. Faber, M. Jarošová, J. Hubácek, P. Slezák, Z. Pikalová & K. Indrák

  2. Institute of Pathology, Medical Faculty, University Palacký, Olomouc, Czech Republic, , , , ,

    D. Riegrová

  3. Institute of Microbiology, Medical Faculty, University Palacký, Olomouc, Czech Republic, , , , ,

    P. Hamal

Authors
  1. E. Faber
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  2. D. Riegrová
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  3. M. Jarošová
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  4. J. Hubácek
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  5. P. Slezák
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  6. Z. Pikalová
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  7. P. Hamal
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  8. K. Indrák
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Received: 26 January 1996 / Accepted: 12 June 1996

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Faber, E., Riegrová, D., Jarošová, M. et al. Abdominal zygomycotic thromboangiitis in a patient with AML and t(1;13;14). Ann Hematol 73, 195–198 (1996). https://doi.org/10.1007/s002770050227

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  • DOI: https://doi.org/10.1007/s002770050227

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