Summary
Results of the BMF study group trials ALL-REZ 83 and 85 for relapsed acute lymphoblastic leukemia (ALL) are presented. For children with late marrow relapse, remission rates of about 90% were seen in both studies. In children treated for early marrow relapse, the remission rate in study ALL-REZ 85 was superior (86% vs 62%). The probability of event-free survival for all patients and for those with early marrow relapse was also statistically significant (P<0.05). Children with T-cell ALL had an extremely unfavourable prognosis in both studies.
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Henze, G., Fengler, R., Hartmann, R. et al. Chemotherapy for bone marrow relapse of childhood acute lymphoblastic leukemia. Cancer Chemother. Pharmacol. 24 (Suppl 1), S16–S19 (1989). https://doi.org/10.1007/BF00253232
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DOI: https://doi.org/10.1007/BF00253232