Abstract
A 17 year old Iranian girl presented with thalassemia major, complicated by acute compression of the cauda equina caused by extramedullary haemopoiesis. The advantages of MRI in confirming the spinal space-occupying lesion and involvement of liver and pancreas are discussed in the context of treatment decision analysis and follow-up.
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References
Caffey J (1985) Pediatric X-Ray diagnosis. Year Book Medical Publishers, Chicago, pp 887–888
Mann KS, Yue CP, Chan KH, Ma LT, Ngan H (1987) Paraplegia due to extramedullary hematopoiesis. J Neurosurg 66: 938–40
Papayasiliou C, Gouliamos A, Vlahos L, Trakadas S, Kalovidouris A, Pouliades G (1990) CT and MRI of symptomatic spinal involvement by extramedullary haematopoiesis. Clin Radiol 42: 91–2
Issaragrisil S, Piankijagum A, Wasi P (1981) Spinal cord compression in thalassemia. Report of 12 cases and recommendations for treatment. Arch Intern Med 141: 1033–1036
Wintrobe MM (1975) Clinical Haematology. 7th Edition. Lea and Febiger, Philadelphia, p 59
Gemenis T, Philippou A, Gouliamos A, Kalovidouris A, Papavasiliou C, Panami A, Chalevelakis G, Papacharalambus X, Raptis S (1989) Atypical location of extramedullary hematopoietic masses in thalassemia. Radiologe 29: 295–6
Gmeinwieser J, Gullotta U, Reiser M, Saida Y, Mack D (1982) Extramedulläre Hämatopoese als Ursache paravertebraler Tumorbildungen im Thorax. RÖFO 137: 68–72
Reif J, Graf N (1989) Spinal space occupying lesions in thalassemia major. Neurosurg Rev 12: 323–31
Ricci C, Cova M, Kang YS, Yang A, Rahmouni A, Scott WW, Zerhouni EA (1990) Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton: MR imaging study. Radiology 177: 83–88
Jackson DV, Randall ME, Richards F (1988) Spinal cord compression due to extramedullary hematopoiesis in thalassemia: long-term follow-up after radiotherapy. Surg Neurol 29: 389–92
Stark DD, Bradley WG (1988) Magnetic resonance imaging. Mosby, St. Louis, p 1123
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Ziegler, L., Lange, M., Feiden, W. et al. Spinal cord compression in thalassemia major: value of MR imaging. Eur. Radiol. 1, 81–84 (1991). https://doi.org/10.1007/BF00540112
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DOI: https://doi.org/10.1007/BF00540112