Abstract
In this study 15 patients with clinical findings and positive cerebrospinal fluid analyses for tuberculous meningitis were evaluated with magnetic resonance imaging (MRI). Tuberculous meningitis was diagnosed in 11 cases when thick meningeal enhancement was present after intravenous injection of gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) in T1-weighted images. Intra-axial tuberculomas were present in 8 patients, 2 of whom had intra-axial tuberculomas without MRI evidence of meningitis. Tuberculomas showed ring or nodular enhancement in postcontrast T1-weighted images, but the most significant MR feature of intraparenchymal tuberculomas was the hypointense appearance of the lesions on T2-weighted images.
Similar content being viewed by others
References
Gupta RK, Jena A, Sharma A, Guha DK, Khushu S, Gupta AK (1988) MR imaging of intracranial tuberculomas. J Comput Assist Tomogr 12: 280.
Kioumehr F, Dadsetan MR, Rooholamini SA, Au A (1994) Central nervous system tuberculosis: MRI. Neuroradiology 36: 93–96.
Sheller JR, Des Prez RM (1986) CNS tuberculosis. Neurol Clin 4: 143.
Pitchenik AE, Cole C, Russell BW (1985) Tuberculosis, atypical mycobacterium, and acquired immunodeficiency syndrome among Haitian and non-Haitian patients in South Florida. Ann Intern Med 101: 641.
Bishburg E, Sunderam G, Reichman LB, Kapila R (1986) Central nervous system tuberculosis with the acquired immunodeficiency syndrome and its related complex. Ann Intern Med 105: 210.
Sellwyn PA, Harted D, Lewis VA et al. (1989) A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N Engl J Med 320: 545.
Parker JC Jr, Dyer MC (1985) Neurologic infections due to bacteria, fungi, and parasites. In: Doris RL, Robertson DM (eds) Textbook of neuropathology. Williams and Wilkins, Baltimore, pp 632–703.
Sze G, Zimmerman RD (1988) The magnetic resonance imaging of infections and inflammatory diseases. Radiol Clin North Am 26: 839.
Mathews VP, Smith RR, Bognanno JR, Kuharik MA, Edwards MK, Harris TM (1989) Gd-DTPA enhanced MR of meningitis: initial clinical experience. AJNR 10: 1290.
Lorber J (1958) Intracranial calcification following tuberculous meningitis in children. Acta Radiol 50: 204.
Tandon PN (1978) Tuberculous meningitis (cranial and spinal). In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 33. North-Holland Publ. Co., Amsterdam, pp 195–262.
Post MJD, Hoffman TA (1984) Cerebral inflammatory disease. In: Rosenberg RN (ed) The clinical neurosciences. Heinz ER (ed) Neuroradiology, vol 4. Churchill Livingstone, New York, pp 525–594.
Goldberg G (1983) Tuberculous infections of the central nervous system. Arizona Med 167: 169.
Hayes WS, Sherman JL, Stern BJ et al. (1987) MR and CT evaluation of intracranial sarcoidosis. AJNR 8: 841.
Talamas O, Del Brutto H, Garcia-Ramos G (1989) Brain-stem tuberculoma: an analysis of 11 patients. Arch Neurol 46: 529.
Salgado P, Del Brutto OH, Talamas O, Zenteno MA, Rodriguez-Carbajal J (1989) Intracranial tuberculoma: MR imaging. Neuroradiology 31: 299.
Chang KH, Han MH, Roh JK et al. (1990) Gd-DTPA enhanced MR imaging in intracranial tuberculosis. Neuroradiology 32: 19.
Zimmerman RD, Becker RD, Devinsky O et al. (1986) Magnetic resonance features of cerebral abscesses and other intracranial inflammatory lesions. Acta Radiol (Suppl) 369: 754.
Whelan MA, Stern J (1981) Intracranial tuberculoma. Radiology 138: 75.
Bawan BC, Post MJD (1991) Intracranial infection. In: Atlas SV (ed) Magnetic resonance imaging of the brain and spine. Raven Press, New York, pp 501–538.
Zimmerman RA (1985) Magnetic resonance imaging of cerebral neoplasms. In: Kressel HY (ed) Magnetic resonance annual. Raven Press, New York, pp 113–148.
Dastur HM (1983) Diagnosis and neurosurgical treatment of tuberculous disease of the CNS. Neurosurgery 6: 111.
Rhoton EL, Ballinger WE, Quisling R, Sypert GW (1988) Intramedullary spinal tuberculoma. Neurosurgery 22: 733.
Author information
Authors and Affiliations
Additional information
Correspondence to: C. Tayfun
Rights and permissions
About this article
Cite this article
Tayfun, C., Üçöz, T., Taşar, M. et al. Diagnostic value of MRI in tuberculous meningitis. Eur. Radiol. 6, 380–386 (1996). https://doi.org/10.1007/BF00180618
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00180618