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Parenchyma-sparing surgery for renal tumors

Experiences in over 120 patients

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Summary

Between 1969 und 1989 conservative surgery for kidney tumors was performed in 123 patients. In 49 patients there was an imperative indication for a parenchyma-sparing operation because nephrectomy would have made dialysis obligatory. Thirty-five of these 49 patients show no signs of tumor progression after a mean follow-up of 4.5 years. Known metastases were present in 3 of 6 patients who died as a result of their tumors. In two patients there was a recurrence after 1 and 5 years, respectively, requiring a second organ-preserving operation. In one further patient we suspect that multiple small tumor lesions may be present 2 years after the first operation. In 74 patients with a healthy contralateral kidney the tumor was enucleated by choice (elective indication). Sixty-eight of these 74 patients show no signs of tumor progression after a mean follow-up period of 3.3 years. One patient died from tumor metastases. Two patients had tumor recurrence, requiring nephrectomy and enucleation, respectively. Fifty-seven enucleated tumors were available for image analysis DNA cytometry. Only the two patients with a hypertriploid tumor died from their cancer.

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Authors and Affiliations

  1. Department of Urology, University of Mainz, Medical School, W-6500, Mainz, Federal Republic of Germany

    F. Steinbach, M. Stöckle, S. Melchior, S. C. Müller, R. Stein & R. Hohenfellner

  2. Department of Pathology, University of Mainz, Medical School, W-6500, Mainz, Federal Republic of Germany

    S. Störkel & R. Stein

  3. Department of Urology, Klinikum Barmen, W-5600, Wuppertal-Barmen, Federal Republic of Germany

    J. W. Thüroff & R. Stein

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  1. F. Steinbach
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  2. M. Stöckle
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  3. J. W. Thüroff
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  4. S. Störkel
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  5. S. Melchior
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  6. S. C. Müller
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  7. R. Stein
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  8. R. Hohenfellner
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Steinbach, F., Stöckle, M., Thüroff, J.W. et al. Parenchyma-sparing surgery for renal tumors. World J Urol 9, 178–183 (1991). https://doi.org/10.1007/BF00182837

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