Abstract
Situs inversus (SI) and the polysplenia syndrome (PS) occur relatively frequently in patients with biliary atresia, the largest subgroup of pediatric liver transplantation patients. We present two cases of orthotopic liver transplantation (OLT) in pediatric patients with SI. One had SI totalis, where a normal liver was placed in the left upper quadrant (LUQ) with the right lobe overlying the vertebral column. The second had PS and isolated SI of the liver, and a living-related left-lateral-segment graft was placed in the LUQ. Although multiple, often unpredictable vascular and intestinal anomalies occur frequently in association with SI, particularly in the setting of the PS, these cases, as well as several others recently reported, reveal that these anomalies can be managed successfully by a variety of technical modifications of the standard OLT technique. Likewise, concerns about the placement of a situs solitus liver in the midline or LUQ position of a SI abdomen have proved to be unfounded.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Accepted: 24 June 1997
Rights and permissions
About this article
Cite this article
Mattei, P., Wise, B., Schwarz, K. et al. Orthotopic liver transplantation in patients with biliary atresia and situs inversus. Pediatr Surg Int 14, 104–110 (1998). https://doi.org/10.1007/s003830050452
Issue Date:
DOI: https://doi.org/10.1007/s003830050452