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Amyloid in a multiple sclerosis lesion is clearly of Aλ type

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Abstract

In rare multiple sclerosis cases amyloid is deposited in demyelinated plaques. In one such case amyloid was examined immunohistochemically with a panel of antibodies directed against different amyloid types. The amyloid was classified as the Aλ type produced by a local monoclonal B cell population.

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Authors and Affiliations

  1. Institute of Pathology, Neuropathology, University of Cologne, Josef-Stelzmann-Strasse 9, 50924 Köln, Germany Fax: +49-221-4786360, , , , , , DE

    R. Schröder

  2. Division of Pathology, Karolinska Institutet, Huddinge Hospital, Huddinge, Sweden, , , , , , SE

    Inger Nennesmo

  3. Max-Planck-Institute of Biochemistry, Martinsried, Germany, , , , , , DE

    Reinhold P. Linke

Authors
  1. R. Schröder
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  2. Inger Nennesmo
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  3. Reinhold P. Linke
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Received: 28 September 1999 / Revised: 17 March 2000 / Accepted: 20 March 2000

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Schröder, R., Nennesmo, I. & Linke, R. Amyloid in a multiple sclerosis lesion is clearly of Aλ type. Acta Neuropathol 100, 709–711 (2000). https://doi.org/10.1007/s004010000244

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  • DOI: https://doi.org/10.1007/s004010000244

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