Summary
Electron microscopic post mortem examination of the lenticular nuclei of two human cases who died in hepatogenic coma is reported. Lesions were found to be swelling and vacuolation of astrocytes. In addition an excess of lipofuscin and lipid like substances were present in the same cells. No changes were found in myelinated fibres, neurons and small blood vessels.
Zusammenfassung
Elektronenmikroskopische Autopsieuntersuchung des Linsenkernes von 2 menschlichen Fällen, die im Leberkoma starben. Als Veränderungen fanden sich Schwellung und Vakuolisierung der Astrocyten. Außerdem waren Lipofuscin- und Lipid-ähnliche Substanzen in den gleichen Zellen vermehrt vorhanden. An den Markfasern, Neuronen und kleinen Blutgefäßen fanden sich keine Veränderungen.
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This study was supported by CIC 80 from Universidad de Concepción.
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Martinez, A. Electron microscopy in human hepatic encephalopathy. Acta Neuropathol 11, 82–86 (1968). https://doi.org/10.1007/BF00692797
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DOI: https://doi.org/10.1007/BF00692797