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Enzyme histochemistry of the chick choroid plexus

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Summary

  1. 1.

    By use of histochemical methods the activity and localization of oxo-reductive enzymes and certain hydrolytic enzymes in chick embryo choroid plexus in between the 35 to 46th stage of development was studied.

  2. 2.

    An increase of enzyme activity with increasing age was found in the choroid plexus with the exception of cytochrome oxidase, which revealed activity of a fairly constant level.

  3. 3.

    The localization of oxoreductive and hydrolytic enzymes on the brush borders of epithelial cells of the choroid plexus especially at the 40th stage of development was prominent.

  4. 4.

    The localization of the various enzyme systems may be related to the active transport phenomena in the choroid plexus.

Zusammenfassung

  1. 1.

    Mittels histochemischer Methoden wurden Aktivität und Lokalisation von oxoreduktiven und gewissen hydrolytischen Enzymen im Plexus chorioideus des Hühnerembryo zwischen dem 35. und 46. Entwicklungsstadium untersucht.

  2. 2.

    Ein Anstieg der Enzymaktivität mit zunehmendem Alter wurde im Plexus chorioideus gefunden; eine Ausnahme bildete die Cytochrom-oxydase, die eine ungefähr gleichbleibende Aktivität zeigte.

  3. 3.

    Auffallend war die Lokalisation der oxoreduktiven und hydrolytischen Enzyme im Bürstenbesatz der Epithelzellen des Plexus chorioideus,-vornehmlich im 40. Entwicklungsstadium.

  4. 4.

    Die Lokalisation verschiedener Enzymsysteme könnte mit den Phänomenen des aktiven Transportes im Plexus chorioideus in Verbindung stehen.

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Authors and Affiliations

  1. National Cancer Institute, Bethesda, Maryland, USA

    J. S. Kaluza (Rockefeller Fellow), M. S. Burstone & I. Klatzo

  2. National Institute of Neurological Diseases and Blindness, Bethesda, Maryland, USA

    J. S. Kaluza (Rockefeller Fellow), M. S. Burstone & I. Klatzo

Authors
  1. J. S. Kaluza
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  2. M. S. Burstone
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  3. I. Klatzo
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Rockefeller Fellow on leave from the Neuropathological Department, Polish Academy of Sciences, Cracow, Poland

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Kaluza, J.S., Burstone, M.S. & Klatzo, I. Enzyme histochemistry of the chick choroid plexus. Acta Neuropathol 3, 480–489 (1964). https://doi.org/10.1007/BF00688456

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  • DOI: https://doi.org/10.1007/BF00688456

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