Summary
A case of primary cerebral rhabdomyosarcoma in a 51-year-old female is reported. The histogenesis of this tumor is discussed. The clinicopathological features of 10 previously reported similar tumors of the CNS are briefly reviewed. Histologically the tumor was polymorphic, but composed of poorly differentiated cells interpreted as rhabdomyoblasts without definite cross-striation. Electron microscopy established that the poorly differentiated cells were of rhabdomyosarcomatous nature, compatible with presumptive myoblasts and analogous to developing fetal muscle.
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Banerjee, A. K., Kak, V. K.: Teratoid tumor of the cerebellum. J. Pathol.111, 285–287 (1973)
Clark, M. A., O'Connel, J.: An ultrastructural study of embryonal rhabdomyosarcoma (sarcoma botryoides) of the bladder. J. Urol.109, 897–900 (1973)
Golman, R. L.: Gliosarcoma of the cerebrum. Am. J. Pathol.52, 741–744 (1969)
Hoffman, S. F., Porke, L. B.: On finding striated muscle in the brain. J. Neurol. Neurosurg. Psychiatry34, 765–771 (1971)
Holimon, J. L., Rosenblum, W. R.: “Gangliorhabdomyosarcoma”. A tumor of ectomesenchyme. Case report. J. Neurosurg.34, 417–422 (1971)
Karcioglue, Z., Someren, A., Mathes, S.: Ectomesenchymoma. A malignant tumor of migratory neural crest (ectomesenchyme) remnants showing ganglionic, schwannian, melanocytic and rhabdomyoblastic differentiation. Cancer39, 2486–2496 (1977)
Koide, O., Ishizone, S.: A case of rhabdomyosarcoma in the brain. Brain Nerve (Tokyo)10, 49–53 (1958) (Japanese)
Leedham, P. W.: Primary cerebral rhabdomyosarcoma and the problem of medullomyoblastoma. J. Neurol. Neurosurg. Psychiatry35, 551–559 (1972)
Legier, J. F., Wells, H. A.: Primary cerebellar rhabdomyosarcoma. Case report. J. Neurosurg.26, 436–438 (1967)
Lopes de Faria, J.: Rhabdomyosarcoma of cerebellum. Arch. Pathol.63, 234–238 (1957)
Lopez, F. S.: Rhabdomyoma als Primärtumor des Kleinhirnbrückenwinkels. Z. Gesamte Neurol. Psychiat.150, 242–251 (1937)
Matsukado, Y., Yokota, A., Marubayashi, T.: Rhabdomyosarcoma of the brain. Case report. J. Neurosurg.43, 215–221 (1975)
Min, K. W., Gyorkey, F., Halpert, B.: Primary rhabdomyosarcoma of the cerebrum. Cancer34, 1405–1411 (1975)
Misugi, K., Med-Sci, D., Liss, L.: Medulloblastoma with crosstriated muscle. A fine structural study. Cancer25, 1279–1285 (1970)
New, P. F. J.: Intracerebral schwannoma. Case report. J.Neurosurg36, 795–797 (1972)
Pasquier, B., Coudere, P., Pasquer, D., Hong, P. M., Pellat, J.: Primary rhabdomyosarcoma of the central nervous system. Acta Neuropathol. (Berl.)33, 333–342 (1975)
Russel, D. S., Rubinstein, L. L.: Pathology of the central nervous system 4th ed., p. 26 London: Arnold 1977
Sarkar, K., Tolnai, G., McKay, D. E.: Embryonal rhabdomyosarcoma of the prostate. An ultrastructural study. Cancer31, 442–448 (1973)
Shuangshoti, S., Piyarath, P., Viriyapanich, P. L.: Primary rhabdomyosarcoma of cerebellum. Necropsy report. Cancer22, 367–371 (1968)
Shuangshoti, S., Netshy, M. G., Jane, J. A.: Neoplasms of mixed mesenchymal and neuroepithelial type. With consideration of the relationship between meningioma and neurilemmoma. J. Neurol. Sci.14, 277–291 (1971)
Shuangshoti, S., Phonprasert, C.: Primary intracranial rhabdomyosarcoma producing proptosis. J. Neurol. Neurosurg. Psychiatry39, 531–535 (1976)
Sima, A., Kindblom, L., Pellettieri, L.: Liposarcoma of the meninges. Acta Pathol. Microbiol Scand [A]84, 306–310 (1976)
Viragh, S., Galambos, J., Juhasz, J.: Heterotopic striated muscle on the surface of the brain. Virchows Arch [Pathol. Anat.]377, 85–89 (1977)
Waga, S., Matsushima, M., Ando, K., Morii, S.: Intracranial chondrosarcoma with extracranial metastasis. Case report. J. Neurosurg.36, 790–794 (1972)
Willis, R. A.: Pathology of the tumors 4th ed., pp. 757–771 London: Butterworth 1967
Woodruff, J. M., Chernik, N. L., Smith, M. C., Millet, W. B., Foote, R. W.: Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant “triton”). Cancer32, 426–439 (1973)
Zimmermann, L. E., Font, R. L., Andersen, S. R.: Rhabdomyosarcomatous, differentiation in malignant intraocular medulloepithelioma. Cancer30, 817–835 (1972)
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Yagishita, S., Itoh, Y., Chiba, Y. et al. Primary rhabdomyosarcoma of the cerebrum. Acta Neuropathol 45, 111–115 (1979). https://doi.org/10.1007/BF00691888
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DOI: https://doi.org/10.1007/BF00691888