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The ultrastructure of the nervous tissue in a benign teratoma

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Summary

The ultrastructure of the nervous tissue in a benign ovarian teratoma is described. This tissue was organized into areas having both “meningel” and “ependymal” surfaces, between which were found astrocytes, ependymal cells, neurones with synapses and microglia. These cells all had ultrastructural similarities to their normal counterparts in the nervous system. In addition, some signs of degenerative change — due possibly to the abnormal location of the nervous tissue — were observed. Oligodendrocytes and myelin were absent, possibly because of vascular insufficiency.

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References

  • Damjanov I, Solter D, Serman D (1973) Teratocarcinoma with the capacity for differentiation restricted to neuro-ectodermal tissue. Virchows Arch [B] 13:179–195

    Google Scholar 

  • González-Cámpora R, Nogales FF Jr, Davidson HG, Mendez JA (1979) Case report: ultrastructure of mature neurogenic implants from ovarian immature teratoma. Histopathology 3:233–240

    Google Scholar 

  • Haugen OA, Taylor CR (1984) Immunohistochemical studies of ovarian and testicular teratomas with antiserum to glial fibrillary acidic protein. Acta Pathol Microbiol Immunol Scand [A] 92:9–14

    Google Scholar 

  • Herman MM, Sipe JC, Rubinstein LJ, VandenBerg SR, Spence AM, Vraa-Jensen J (1975). An experimental mouse testicular teratoma as a model for neuroepithelial neoplasia and differentiation. II. Electron microscopy. Am J Pathol 81:421–444

    Google Scholar 

  • Kennedy C, Grave GD, Jehle JW, Sokoloff L (1970) Blood flow to white matter during maturation of the brain. Neurology 20:613–618

    Google Scholar 

  • Kennedy C, Sakurada O, Shinohara M, Miyaoka M, Sokoloff L (1979) A comparison of the rates of local cerebral glucose utilization in new-born and pubescent monkeys. Ann Neurol 6:176 [abstr]

    Google Scholar 

  • Luse SA, Vietti T (1968) Ovarian teratoma. Ulttrastructure and neural component. Cancer 21:38–51

    Google Scholar 

  • Nogales FF Jr, Aguilar D (1983) Neural tissue in human teratomas. In: Damjanov I, Knowles BB, Solter D (eds) The human teratoma. Experimental and clinical biology. Humana Press, Clifton, pp 173–190

    Google Scholar 

  • Nogales FF Jr, Fernandez-Sanz J, Rivera-Huerto F, Matilla A, Galera H (1979) Estudio clínicopatológico de 288 teratomas quísticos del ovario. Patología (Mex City) 16:11–25

    Google Scholar 

  • Pappas C (1981) CNS myelin and synapses in a spontaneous mouse ovarian teratoma showing neural differentiation. An immunohistochemical and electron microscopic study. J Neuropathol Exp Neurol 40: 289–297

    Google Scholar 

  • Pesce C, Tobia F, Scott T (1985) Microglia in teratomas. Acta Neuropathol (Berl) 67:332–336

    Google Scholar 

  • Tresman RL, Evans MJ (1975) A light and electron microscopical study of the nervous tissue of mouse teratomas. J Neurocytol 4:301–314

    Google Scholar 

  • Trojanowski JQ, Hickey WF (1984) Human teratomas express differentiated neural antigen. An immunohistochemical study with anti-neurofilament, anti-glial filament, and antimyelin basic protein monoclonal antibodies. Am J Pathol 115:383–389

    Google Scholar 

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Scott, T., Pesce, C. The ultrastructure of the nervous tissue in a benign teratoma. Acta Neuropathol 73, 281–286 (1987). https://doi.org/10.1007/BF00686623

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  • DOI: https://doi.org/10.1007/BF00686623

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