Summary
In this study we evaluated the relationship between polyglucosan bodies and peripheral nerve lesions. The biopsied sural nerve from a patient with late-onset chronic sensori-motor neuropathy showed many intra-axonal polyglucosan bodies and segmental demyelination/remyelination. The formation of Schwann cell hyperplasia around the demyelinated axons was found at the sites of polyglucosan bodies. These findings suggest that demyelinating neuropathy is a part of the spectrum of the diseases characterized by the accumulation of polyglucosan bodies within cellular compartments.
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Matsumuro, K., Izumo, S., Minauchi, Y. et al. Chronic demyelinating neuropathy and intra-axonal polyglucosan bodies. Acta Neuropathol 86, 95–99 (1993). https://doi.org/10.1007/BF00454906
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DOI: https://doi.org/10.1007/BF00454906