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Glycerol effects on the transport of macromolecules in the lateral cochlear wall

An HRP study in the guinea pig

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Summary

The effect has been studied of intravenously administered glycerol on paracellular and cellular transport of macromolecular HRP tracer in the lateral cochlear wall. The findings indicate osmotically induced diffusion phenomena by the opening of shunt pathways through junctional complexes in the stria vascularis. Vesicular transport is accelerated, direction of transport however is not affected by the changed osmolality.

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Authors and Affiliations

  1. Clinic and Polyclinic of Otorhinolaryngology, University of Munich, Federal Republic of Germany

    K. Mees

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  1. K. Mees
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Supported by the Deutsche Forschungsgemeinschaft (Me 785/1-3)

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Mees, K. Glycerol effects on the transport of macromolecules in the lateral cochlear wall. Arch Otorhinolaryngol 239, 49–59 (1984). https://doi.org/10.1007/BF00454262

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  • DOI: https://doi.org/10.1007/BF00454262

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