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Zur Frage der Brauchbarkeit isolierter Mastzellen aus Adenoiden zur Diagnose von Inhalationsallergien

Suitability of isolated mast cells from adenoids for the diagnosis of inhalatory allergies

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Summary

The enzymic tissue dispersion method yields single mast cells from human adenoids. These cells are light- and electronmicroscopically intact. The mast cells react to the calcium-ionophor A 23187 and to anti-human-immunglobulin E or acetylcholine after passive sensitization with histamine release. After passive sensitization with serum of patients suffering from hay feaver the specific antigen induces a histamine release.

Isolated mast cells prove to be a simple system to diagnose allergies and to test antiallergic drugs in human material.

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  1. Aachen

    P. Pult, C. Rauch a. G., W. Schönfeld a. G. & W. Schmutzler a. G.

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  1. P. Pult
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  2. C. Rauch a. G.
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  3. W. Schönfeld a. G.
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  4. W. Schmutzler a. G.
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Pult, P., Rauch, C., Schönfeld, W. et al. Zur Frage der Brauchbarkeit isolierter Mastzellen aus Adenoiden zur Diagnose von Inhalationsallergien. Arch Otorhinolaryngol 219, 432 (1978). https://doi.org/10.1007/BF00463879

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  • DOI: https://doi.org/10.1007/BF00463879

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