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Rasterelektronenmikroskopische Untersuchungen an fibrösen und fibro-gliösen epiretinalen Fibroplasien

Studies on fibrous and fibro-glial surface wrinkling retinopathy by scanning electron microscopy

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Summary

The scanning electron microscope was used to examine 16 cases of epiretinal membrane formation and retinal puckers which occurred in a variety of primary retinal disorders. In this first section the authors describe three types of epiretinal membranes: (1) Fibrous acellular membranes with and without vitreous adhesions. Retinal puckering was caused by vitreous traction with collagen strands binding the residual folds. (2) Fibrous membranes containing isolated glial cells. (3) Fibrous membranes partly covered by sheets of glial cells.

In all three forms the acellular fibrous component is believed to represent vitreous cortex remnants. The invariable presence of these fibrous membranes at sites of retinal pucker and their relationship to wrinkled internal limiting membrane suggests that contraction of these membranes is responsible for retinal puckering. Morphological evidence of glial membrane contraction and collagen production by glial cells was not found.

Zusammenfassung

Es werden die rasterelektronenmikroskopischen Befunde von 16 epiretinalen Fibroplasien mit Netzhautfältelung nach verschiedenen primären Funduserkrankungen dargestellt. In diesem ersten Teil besprechen die Autoren: 1. Fibröse, zellfreie epiretinale Membranen mit und ohne strangförmige Glaskörperadhärenzen. Die Fältelung der Retina kommt durch Glaskörpertraktion und Faserbrücken zustande. 2. Fibröse Membranen, welchen einzelne Gliazellen ein- und aufgelagert sind, ohne daß Zellmembranen entstehen. Auch hier wird die Fältelung durch Kollagenfaserbrücken verursacht. 3. Fibröse Membranen, denen gebietsweise Gliamembranen aufgelagert sind. Die Fasermembranen aller drei Typen werden als residuale Glaskörperrinde interpretiert. Weil sie über allen Faltenherden vorhanden sind und wegen ihrem Verhalten zu den Limitansfalten wird angenommen, daß ihre Kontraktion Ursache der Netzhautfältelung ist. Morphologische Anhaltspunkte für Kontraktion von Gliamembranen oder Faserbildung durch die Glia wurden nicht gefunden.

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Frl. Haberkorn, Frau Wagner und Frau Exinger gilt der Dank für ihre technische, administrative und fotografische Mithilfe.

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Daicker, B., Guggenheim, R. Rasterelektronenmikroskopische Untersuchungen an fibrösen und fibro-gliösen epiretinalen Fibroplasien. Albrecht von Graefes Arch. Klin. Ophthalmol. 207, 229–242 (1978). https://doi.org/10.1007/BF00431162

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