Summary
Quantitative and qualitative examination of Polychlorinated Biphenyl (PCB) residues in blood of the women occupationally exposed to PCBs and of their children has been carried out. The children examined in this study have ingested their mothers' milk for periods of 0 to 3 years. The age of the children at the time of this study ranges from 0 to 13 years. The data obtained in this examination provide evidence that PCBs are retained in the children's body for many years and a longer feeding of mothers' milk tends to increase PCB levels in the blood of the children. Especially high PCB levels, 93.2 ppb (μg/kg) and 77.4 ppb are found in the blood of two children. It is found that the gas chromatographic patterns of blood PCBs of the children who have been fed on their mothers' milk for a long time, are different from those of their mothers.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Acker, L., Schulte, E.: Über das Vorkommen von chlorierten Biphenylen und Hexachlorobenzol neben chlorierten Insektiziden in Humanmilch und menschlichem Fettgewebe. Naturwissenschaften57, 497 (1970)
Biros, F. J., Walker, A. C., Medbery, A.: Polychlorinated biphenyls in human adipose tissue. Bull. Environ. Contam. Toxicol.5, 317–323 (1970)
Hara, I., Kuwabara, K., Kunita, N., Harada, A., Umeda, G.: Survey of the physical condition of the children whose mothers were occupationally exposed to PCBs. Proceedings of Annual Meeting of Japanese Society of Public Health (Gifu, Japan) p. 619 (1976)
Jensen, S., Johnels, A. G., Olsson, M., Otterlind, G.: DDT and PCB in marine animals from Swedish waters. Nature224, 247–250 (1969)
Jensen, S., Sundström, G.: Structures and levels of most chlorobiphenyls in two technical PCB products and in human adipose tissue. AMBIO3, 70–76 (1974)
Kuratsune, M., Morikawa, Y., Hirohata, T., Nishizumi, M., Kohchi, S., Yoshimura, T., Matsuzaka, J., Yamaguchi, A., Saruta, N., Ishinishi, N., Kunitake, E., Shimono, O., Takigawa, K., Oki, K., Sonoda, M., Ueda, T., Ogata, M.: An epidemiologic study on „Yusho” or chlorobiphenyls poisoning. Fukuoka Acta Med.60, 513–532 (1969)
Kuwabara, K., Yakushiji, T., Watanabe, I., Yoshida, S., Yoshida, Y., Murata, H., Koyama, K., Kunita, N.: Studies on polychlorinated biphenyls (PCBs) in the blood of Yusho patients (3rd report). Pro. Osaka Pref. Inst. Publ. Health (Ed. Food Sanitation) 8, 83–86 (1977 A)
Kuwabara, K., Yakushiji, T., Watanabe, L, Yoshida, S., Koyama, K., Kunita, N.: PCB residues in blood of mothers and their children fed on human milk. Pro. Osaka Pref. Inst. Publ. Health (Ed. Food Sanitation) 8, 79–82 (1977 B)
Masuda, Y., Kagawa, R., Kuratsune, M.: Comparison of polychlorinated biphenyls in Yusho patients and ordinary persons. Bull. Environ. Contam. Toxicol.11, 213–216 (1974)
Mizutani, T., Matsumoto, M., Fujiwara, K., Igaku no Ayumiy81, 666–667 (1972)
Nakamura, A., Kashimoto, T.: Studies on a calculation method for polychlorinated biphenyl (PCB) isomers, Analysis by Apiezon L column. J. Food Hyg. Soc. Japan18, 1–12 (1977)
Price, H. A., Welch, R. L.: Occurrence of polychlorinated biphenyls in humans. Environ. Hlth. Perspectives1, 73–78 (1972)
Risebrough, R. W., Rieche, P., Peakell, D. B., Herman, S. G., Kirven, M. N.: Polychlorinated biphenyls in the global ecosystem. Nature220, 1098–1102 (1968)
Takagi, Y., Otake, T., Kataoka, M., Murata, Y., Aburada, S., Akasaka, S., Hashimoto, K., Uda, H., Kitaura, T.: Studies on the transfer and distribution of (14C) polychlorinated biphenyls from maternal to fetal and suckling rats. Toxicol. Appl. Pharmacol.38, 549–558 (1976)
Takamatsu, M., Inoue, Y., Abe, S.: Diagnostic meaning of the blood PCB. Fukuoka Acta Med.65, 28–31 (1974)
Ugawa, M., Nakamura, A., Kashimoto, T.: Studies on a calculation method for polychlorinated biphenyl isomers (PCBs). In: “New methods in environmental chemistry and toxicology,” the international symposium on ecological chemistry, Susano, Japan (F. Coulston et al. eds.), p. 253–267, Totsuka, Tokyo, Japan: International Academic Printing 1973
Umeda, G.: PCB poisoning in Japan. AMBIO1, 132–134 (1972)
Watanabe, I., Yakushiji, T., Kuwabara, K., Yoshida, S., Koyama, K., Hara, I., Kunita, N.: Studies on PCBs in blood of ordinary persons, Yusho patients and occupationally exposed workers. Jap. J. Publ. Health24, 749–756 (1977)
Yakushiji, T., Watanabe, I., Kuwabara, K., Yoshida, S., Koyama, K., Kunita, N.: Residues of polychlorinated biphenyls and organochlorine pesticides in human milk, blood and diet (V). Pro. Osaka Pref. Inst. Publ. Health (Ed. Food Sanitation)8, 35–44 (1977 A)
Yakushiji, T., Watanabe, L, Kuwabara, K., Yoshida, S.: Identification by GC-MS of low-chlorinated biphenyls in mothers' milk. J. Chromatogr. (in press, 1977 B)
Yoshida, S., Yakushiji, T., Watanabe, I., Kuwabara, K., Koyama, K., Kunita, N.: Studies on PCB pattern in rats administered KC-300. Pro. Osaka Pref. Inst. Publ. Health (Ed. Food Sanitation)8, 59–66 (1977)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kuwabara, K., Yakushiji, T., Watanabe, I. et al. Relationship between breast feeding and PCB residues in blood of the children whose mothers were occupationally exposed to PCBs. Int. Arch Occup Environ Heath 41, 189–197 (1978). https://doi.org/10.1007/BF00572891
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00572891