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Aromatic DNA adducts in white blood cells of coke workers

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Summary

White blood cell DNA adducts were measured in coke workers, local controls and countryside controls using the 32P-postlabelling technique. The method detected aromatic adducts including those formed by polycyclic aromatic hydrocarbons (PAHs). Coke workers are heavily exposed to PAHs particularly when working at the batteries. A difference in adduct levels was noted between the coke workers at the battery as compared to other jobs. The adduct levels in the non-battery were higher than those in the countryside controls.

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Hemminki, K., Grzybowska, E., Chorazy, M. et al. Aromatic DNA adducts in white blood cells of coke workers. Int. Arch Occup Environ Heath 62, 467–470 (1990). https://doi.org/10.1007/BF00379065

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  • DOI: https://doi.org/10.1007/BF00379065

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