Skip to main content
Log in

Work in operating rooms and pregnancy outcome among nurses

  • Original Article
  • Published:
International Archives of Occupational and Environmental Health Aims and scope Submit manuscript

Abstract

The aim of this study was to analyse the relationship between work in an operating room and pregnancy outcome, as described by the rates of spontaneous abortion and of birth defects. The population comprised the female nurses of 17 hospitals in Paris, interviewed in 1987–1989. An exposed group included all operating room nurses, and a control group was composed of female nurses in other departments matched by hospital, age and duration of service. Each woman described all prior pregnancies. In total, 776 pregnancies were described by 418 nurses who were first pregnant in 1970 or thereafter; ectopic pregnancies, those terminated by voluntary induced abortion and those leading to multiple births were excluded. The rate of spontaneous abortion was significantly higher for pregnancies during which women worked in an operating room than for the other pregnancies. Birth defects were not significantly related to work in an operating room during pregnancy. These results are in agreement with others showing a significant relationship between occupational exposure to operating rooms and spontaneous abortion, although identification of the responsible factor remains difficult. They suggest that effective ventilating systems should be installed in all operating rooms and that special preventive measures must be taken for women of childbearing age.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Armstrong BG, McDonald A, Sloan M (1992) Cigarette, alcohol, and coffee consumption and spontaneous abortion. Am J Public Health 82:85–87

    Google Scholar 

  2. Axelsson G, Rylander R (1982) Exposure to anaesthetic gases and spontaneous abortion: response bias in a postal questionnaire study. Int J Epidemiol 11:250–256

    Google Scholar 

  3. Bonney GE (1987) Logistic regression for dependent binary observations. Biometrics 43:951–973

    Google Scholar 

  4. Bruce DL, Eide KA, Linde HW, Eckenhoff JE (1968) Causes of death among anesthesiologists: a 20-year study. Anesthesiology 29:565–569

    Google Scholar 

  5. Chang LW, Katz J (1976) Pathologic effects of chronic halothane inhalation: an overview. Anesthesiology 45:640–653

    Google Scholar 

  6. Cohen EN, Brown BW, Bruce DL, et al. (1974) Occupational disease among operating room personnel: a national study. Anesthesiology 41:321–340

    Google Scholar 

  7. Cohen EN, Brown BW, Wu ML, et al. (1980) Occupational disease in dentistry and chronic exposue to trace anesthetic gases. J Am Dent Assoc 101:21–31

    Google Scholar 

  8. Corbett TH, Cornell RG, Endres JL, Lieding K (1974) Birth defects among children of nurse-anesthetists. Anesthesiology 41:341–344

    Google Scholar 

  9. Dang Vu B, Estryn-Behar M, Monad G, Saint-Maurice Cl (1992) Theatre staff members and exposure to halogenated agents. Pediatr Anaesth 2:279–284

    Google Scholar 

  10. Ericson A, Källen B (1979) Survey of infants born in 1973 or 1975 to Swedish women working in operating rooms during their pregnancies. Anesth Analg 58:302–305

    Google Scholar 

  11. Gardner RJ (1989) Inhalation anaesthetics — exposure and control: a statistical comparison of personal exposures in operating theatres with and without anaesthetic gas scavenging. Ann Occup Hyg 33:159–173

    Google Scholar 

  12. Guirguis SS, Pelmear PL, Roy ML, Wong L (1990) Health effects associated with exposure to anaesthetic gases in Ontario hospital personnel. Br J Ind Med 47:490–497

    Google Scholar 

  13. Hemminki K, Axelson O, Niemi ML, Ahlborg G (1983) Assessment of methods and results of reproductive occupational epidemiology: spontaneous abortions and malformations in the offspring of working women. Am J Ind Med 4:293–307

    Google Scholar 

  14. Hemminki K, Kyyrönen P, Lindbohm ML (1985) Spontaneous abortions and malformations in the offspring of nurses exposed to anaesthetic gases, cytostatic drugs, and other potential hazards in hospitals, based on registered information of outcome. J Epidemiol Community Health 39:141–147

    Google Scholar 

  15. Hemminki K, Hemminki E, Lindbohm ML, Taskinen H (1990) Exogenous causes of spontaneous abortion. In: Huisjes H, Lind T (eds) Early pregnancy failure. Churchill Livingstone, London

    Google Scholar 

  16. Knill-Jones RP, Rodrigues LV, Moir DD, Spence AA (1972) Anaesthetic practice and pregnancy: controlled survey of women anaesthetists in the United Kingdom. Lancet 1:1326–1328

    Google Scholar 

  17. Lauwerys R, Siddons M, Misson CB, et al. (1981) Anaesthetic health hazards among Belgian nurses and physicians. Int Arch Occup Environ Health 48:195–203

    Google Scholar 

  18. McDonald A, McDonald JC, Armstrong B, Cherry NM, Côté R, Lavoie J, Nolin AD, Robert D (1988) Congential defects and work in pregnancy. Br J Ind Med 45:581–588

    Google Scholar 

  19. Pharoah POD, Alberman E, Doyle P, Chamberlain G (1977) Outcome of pregnancy among women in anaesthetic practice. Lancet 1:34–36

    Google Scholar 

  20. Roman E (1984) Fetal loss rates and their relation to pregnancy order. J Epidemiol Commmunity Health 38:29–35

    Google Scholar 

  21. Saurel-Cubizolles MJ, Estryn-Behar M, Maillard MF, Mugnier N, Masson A, Monod G (1992) Neuropsychological symptoms and occupational exposure to anaesthetics. Br J Ind Med 49:276–281

    Google Scholar 

  22. Saurel-Cubizolles MJ, Estryn-Behar M, Maillard MF, Mugnier N, Monod G (1992) Working conditions for operating theatre staff. In: Estryn-Behar M, Gadbois C, Pottier M. Hospital ergonomics. Octares Editions, Toulouse, pp 209–214

  23. Saurel-Cubizolles MJ, Job-Spira N, Estryn-Behar M (1993) Ectopic pregnancy and occupational exposure to antineoplastic drugs. Lancet 341:1169–1171

    Google Scholar 

  24. Selevan SG, Lindbohm ML, Hornung RW, Hemminki K (1985) A study of occupational exposure to antineoplastic drugs and fetal loss in nurses. N Engl J Med 313:1173–1178

    Google Scholar 

  25. Skov T, Maarup B, Olsen J, Rorth M, Winthereik H, Lynge E (1992) Leukaemia and reproductive outcome among nurses handling antineoplastic drugs. Br J Ind Med 49:855–861

    Google Scholar 

  26. Stücker I, Caillard JF, Collin R, Gout M, Poyen D, Hémon D (1990) Risk of spontaneous abortion among nurses handling antineoplastic drugs. Scand J Work Environ Health 16:102–107

    Google Scholar 

  27. Taskinen H, Lindbohm ML, Hemminki K (1986) Spontaneous abortions among women working in the pharmaceutical industry. Br J Ind Med 43:199–205

    Google Scholar 

  28. Wilcox AJ, Weinberg RC, Baird DD (1990) Risk factors for early pregnancy loss. Epidemiology 1:382–385

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saurel-Cubizolles, M.J., Hays, M. & Estryn-Behar, M. Work in operating rooms and pregnancy outcome among nurses. Int. Arch Occup Environ Heath 66, 235–241 (1994). https://doi.org/10.1007/BF00454361

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00454361

Key words

Navigation