Summary
A case of disseminated trichosporonosis associated with Candida infection of the urinary bladder is presented. Coffee bean shaped or crescent shaped yeast-like elements are characteristic of Trichosporon and useful in differentiating Trichosporon fromCandida but such histological features are less efficient than the immunohistochemistry in identifing mixed fungal infection. In the present case, an application of avidin-biotin-complex (ABC) method with anti -Trichosporon antiserum and anti-Candida antiserum enabled us to diagnose a mixed infection by both fungi.
Similar content being viewed by others
References
Cooper BH, Silva-Hutner M (1985) Yeasts of medical importance. In: Lennette EH, Balows A, Hausler WJ Jr, Shadomy HJ (eds) Manual of clinical microbiology, 4th edition. American Society for Microbiology, Washington, DC, pp 538–539
Dermoumi H (1979) Differentiation of yeast like fungi isolated from clinical specimens with the API 20 C Auxanogramm. Arztl Lab 25:289–291
Evans HL, Kletzel M, Lawson RD, Frankel LS, Hopfer RL (1980) Systemic mycosis due to Trichosporon cutaneum. Cancer 45:367–371
Gold JWM, Poston W, Mertelsmann R, Lange M, Kiehn T, Edwards F, Bernard E, Christiansen K, Armstrong D (1981) Systemic infection with Trichosporon cutaneum in a patient with acute leukemia: report of a case. Cancer 48:2163–2167
Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577–580
Hoy J, Hsu K-C, Rolston K, Hopfer RL, Luna M, Bodey GP (1986) Trichosporon beigelii infection: a review. Rev Infect Dis 8:959–967
Kirmani N, Tuazon CV, Geelhoed GW (1980) Disseminated Trichosporon infection: occurrencein an immunosuppressed patient with chronic active hepatitis. Arch Int Med 140:277–278
Kobayashi M, Kotani S, Fujishita M, Taguchi H, Moriki T, Enzan H, Miyoshi I (1988) Immunohistochemical identification of Trichosporon beigelii in histologic section by immunoperoxidase method. Am J Clin Pathol 89:100–105
Mochizuki T, Sugiura H, Watanabe S, Takada M, Hodohara K, Kushima R (1989) A case of disseminated trichosporonosis: A case report and immunohistochemical identification of fungal elements. J Med Vet Mycol 26:343–349
Mori T, Kohara T, Matsumura M, Hirano T, Wakabayashi Y, Ikemoto H, Watanabe A, Yumura W, Sakamoto Y, Shirai T, Kume H (1988) A case of polymycotic septicemia caused by Trichosporon beigelii, Candida albicans and Candida Kurusei. Jpn J Med Mycol 29:120–126
Rivera R, Cangir A (1975) Trichosporon sepsis and leukemia. Cancer 36:1106–1110
Saul SH, Khachatoorian T, Poorsattar A, Myerowitz RL, Geyer SJ, Pasculle AW, Ho M (1981) Opportunistic Trichosporon pneumonia. Arch Pathol Lab Med 105:456–459
Walsh TJ, Newman KR, Moody M, Wharton RC, Wade JC (1986) Trichosporonosis in patients with neoplastic disease. Medicine 65:268–279
Yung CW, Hanauer SB, Fretzin D, Rippon JW, Shapiro C, Gonzalez M (1981) Disseminated Trichosporon beigelii (cutaneum). Cancer 48:2107–2111s
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kimura, M., Takahashi, H., Satou, T. et al. An autopsy case of disseminated trichosporonosis with candidiasis of the urinary bladder. Vichows Archiv A Pathol Anat 416, 159–162 (1989). https://doi.org/10.1007/BF01606321
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01606321