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Studies on dentinogenesis in the rat

Ultrastructural observations on early dentin formation with special reference to “Dentinal globules” and alkaline phosphatase activity

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Summary

At the submicroscopic level, extracellular globular membrane-delimited structures have been observed in the matrix in early dentin formation in the rat. Within these “dentinal globules”, needle-like crystallites are found before apatite crystals appear in the filamentous-amorphous ground substance. In sections incubated for alkaline phosphatase, reaction products are closely associated with these globules. The possible role of the globules in initial dentin formation is discussed.

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Larsson, Å. Studies on dentinogenesis in the rat. Z. Anat. Entwickl. Gesch. 142, 103–115 (1973). https://doi.org/10.1007/BF00519879

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