Summary
The recessive mutation, rachiterata, reduces the number of cervical vertebrae to 6 by shifting the cervico-thoracic boundary in a cranial direction, and produces partial duplication of the neural arch of the axis. Rachiterata also produces malformations of thoraco-lumbar vertebrae, often associated with fusions of ribs. These malformations are caused by a disturbed arrangement of somites first detectable in 11-day embryos.
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References
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Supported in part by NIH research grant CA02662 from the National Cancer Institute.
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Theiler, K., Varnum, D. & Stevens, L.C. Development of rachiterata, a mutation in the house mouse with 6 cervical vertebrae. Z. Anat. Entwickl. Gesch. 145, 75–80 (1974). https://doi.org/10.1007/BF00519127
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DOI: https://doi.org/10.1007/BF00519127