Summary
Cilia 9+0 have been found in differentiating neurosecretory neurons of the hypothalamic supraoptic nuclei of Wistar rats. These ciliated neurosecretory cells were always observed during the neonatal period of the rat and no more than one cilium per cell has been encountered.
Single cilia arising from typical basal bodies were usually located in deep invaginations of the neuronal perikaryon, but can also be seen in superficial positions. Their basal bodies were commonly found in the vicinity of Golgi complexes, and associated structures such as striated rootlets and alar sheets were also present. In addition, single centrioles frequently appeared in these neurons, occurring close to basal bodies but also in centrosomatic areas.
The respective roles of these morphological features are suggested and their possible ontogenetic significance is briefly discussed.
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References
Afzelius BA (1969) Ultrastructure of the cilia and flagella. In: A Lima-de Faria (ed.) Handbook of molecular cytology pp 1219–1242. North-Holland, Amsterdam
Allen RA (1965) Isolated cilia in inner retinal neurons and in retinal pigment epithelium. J Ultrastruct Res Suppl 12:703–747
Altman J, Bayer SA (1978) Development of diencephalon in the rat. I. Autoradiographic study of the time of origin and settling patterns of neurons of the hypothalamus. J Comp Neurol 182:945–972
Anderson RGW (1972) The three-dimensional structure of the basal body from the rhesus monkey oviduct. J Cell Biol 54:246–265
Choy VJ, Watkins WB (1979) Maturation of the hypothalamo-neurohypophysial system. I. Localization of neurophysin, oxytocin and vasopressin in the hypothalamus and neural lobe of the developing rat brain. Cell Tissue Res 197:325–336
Currie AR, Wheatley DN (1966) Cilia of a distinctive structure (9+0) in endocrine and other tissues. Postgrd Med J 42:403–408
Dahl HA (1963) Fine structure of cilia in rat cerebral cortex. Z Zellforsch 60:369–386
Dawson AB (1953) The early appearance of secretion in the neurohypophysis and hypothalamic nuclei of the rat. Anat Rec 114:620–630
Del Cerro MP, Snider RS (1967) Cilia in the cerebellum of immature and adult rats. J Microsc 6:515–518
Dustin P, Anjo A, Flament-Durand J (1979) Centriologenesis and ciliogenesis in rat pituicytes. Biol Cellulaire 34:227–236
Eneström S (1967) Nucleus supraopticus, a morphological and experimental study in the rat. Acta Pathol Microbiol Scand Suppl 186:1–99
Fawcett DW (1961) Cilia and flagella. In: J Brachet, AE Mirsky (eds) The Cell, vol II pp 217. Academic Press, New York and London
Flood R, Totland GK (1977) Substructure of solitary cilia in mouse kidney. Cell Tissue Res 183:281–290
Fonte VG, Searls RI, Hilfer SR (1971) The relationship of cilia with cell division and differentiation. J Cell Biol 49:226–229
Gould RR, Borisy GG (1977) The pericentriolar material in chinese hamster ovary cells nucleates microtubule formation. J Cell Biol 73:601–615
Karlsson U (1966) Three-dimensional studies of neurons in the lateral genculate nucleus of the rat. I. Organelle organization in the perikarion and its proximal branches. J Ultrastruct Res 16:429–481
Kemali M, Gioffré D (1978) Non-ependymal cilia in the habenulae and the interpeduncular nucleus of the frog tadpole. Cell Tissue Res 195:527–533
Meier-Vismara E, Walker N, Vogel A (1979) Single cilia in the articular cartilage of the cat. Expl. Cell Biol 47:161–171
Myklebust R, Engedal H, Saetersdal TH, Ulstein M (1977) Primary 9+0 cilia in the embryonic and the adult human heart. Anat Embryol 151:127–139
Palay SL (1961) Structural peculiarities of the neurosecretory cells in the preoptic nucleus of the goldfish, Carassius auratus. Anat Rec 139:262
Rash EJ, Shay JW, Biesele JB (1969) Cilia in cardiac differentiation. J Ultrastruct Res 29: 470–484
Scharrer E (1962) Electron microscopy of neurosecretory cells in the preoptic nucleus of the toadfish (Opsanus tau). Biol Bull 123:461–462
Sorokin S (1962) Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells. J Cell Biol 15:363–377
Vigh-Teichmann I, Vigh B, Aros B (1976a) Cerebrospinal fluid-contacting neurons, ciliated perikarya and “peptidergig” sinapses in the magnocellular preoptic nucleus of teleostean fishes. Cell Tissue Res 165:397–413
Vigh-Teichmann I, Vigh B, Aros B (1976b) Ciliated neurons and different types of synapses in anterior hypothalamic nuclei of reptiles. Cell Tissue Res 174:139–160
Wheatley DN (1967) Cilia and centrioles of the rat adrenal cortex. J Anat 101:223–237
Zeligs JD, Wollman SH (1979) Mitosis in rat thyroid epithelial cells in vivo. II. Centrioles and pericentriolar material. J Ultrastruct Res 66:97–108
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Lafarga, M., Hervás, JP., Crespo, D. et al. Ciliated neurons in supraoptic nucleus of rat hypothalamus during neonatal period. Anat. Embryol. 160, 29–38 (1980). https://doi.org/10.1007/BF00315647
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DOI: https://doi.org/10.1007/BF00315647