Summary
Perichromatin granules, nematosomes (threadlike bodies), or concentric lamellar bodies were rarely observed in profiles of principal ganglionic neurons in the untreated rat superior cervical ganglion. They were more frequenlty encountered in these neurons following long-term activation of the sympathetic nervous system by intermittent immobilization (6 to 18 12-h periods). The increased number of the described nuclear and cytoplasmic structures following immobilization is documented by morphometric data and discussed in relation to specific chronic neuronal hyperactivity.
Similar content being viewed by others
References
Anzil A, Herrlinger H, Blinzinger K (1973) Nucleolus-like inclusions in neuronal perikarya and processes: Phase and electron microscope observations on the hypothalamus of the mouse. Z Zellforsch 146:329–337
Bernhard W, Granboulan N (1968) Electron microscopy of the nucleolus in vertebrate cells. In: (Dalton AJ, haguenau F, eds) Ultrastructure in biological systems, Vol 3: The nucleus. Academic Press, New York and London, pp 81–150
Buschmann T (1979) Development of lamellar bodies and subsurface cisterns in pyramidal cells and neuroblasts of hamster cerebral cortex. Am J Anat 155:175–183
Dallner G, Siekevitz P, Palade GE (1966) Biogenesis of endoplasmic reticulum membranes. I. Structural and chemical differentiation in developing rat hepatocyte. J Cell Biol 30:73–96
Dupuy-Coin AM, Kalifat SR, Bouteille M (1972) Nuclear bodies as proteinaceous structures containing ribonucleoproteins. J Ultrastruct Res 38:174–187
Forssmann WG (1964) Studien über den Feinbau des Ganglion cervicale superius der Ratte. I. Normale Struktur. Acta Anat 59:106–140
Gambetti P, Gonatas NK, Flexner LB (1968) The fine structure of puromycin-induced changes in mouse entorhinal cortex. J Cell Biol 36:379–390
Ghadially FN (1975) Concentric lamellar bodies. In: (Ghadially FN, ed) Ultrastructural pathology of the cell. Butterworth, London and Boston, pp 266–271
Grillo MA (1970) Cytoplasmic inclusions resembling nucleoli in sympathetic neurons of adult rats. J Cell Biol 45:100–117
Heym Ch, Addicks K, Wedel Ch (1981) Effect of intermittent immobilization on the ultrastructure of the rat superior cervical ganglion. J Auton Nerv Syst 4:283–296
Kessel RG (1968) Annulate lamellae. J Ultrastruct Res Suppl 10:1–82
Kishi K (1972) Fine structural and cytochemical observations on cytoplasmic nucleoluslike bodies in nerve cells of rat medulla oblongata. Z Zellforsch 132:523–532
Leduc J (1961) Catecholamine production and release in exposure and acclimation to cold. Acta Physiol Scand 53: Suppl 183:1–161
Matthews MR, Raisman G (1972) A light and electronmicroscopic study of the cellular response to axonal injury in the superior cervical ganglion of the rat. Proc R Soc Lond B 181:43–79
Moyne G, Nash RE, Puvion E (1977) Chromatin granules in isolated rat hepatocytes treated with cortisol and cycloheximide. Biol Cellulaire 30:5–16
Nickerson PA (1972) Effect of testosterone, dexamethasone and hypophysectomy on membranous whorls in the adrenal gland of the mongolian gerbil. Anat Rec 174:191–204
Nickerson PA (1977) Formation of concentric whorls of rough endoplasmic reticulum in the adrenal gland of the mongolian gerbil. J Anat 124:282–391
Palay S, Palade GE (1955) The fine structure of neurons. J Biophys Biochem Cytol 1:69–88
Porter KR (1961) The ground substance: observation from electron microscopy. In: (Brachet J, Mirsky AE, eds) The cell. Academic press, New York, Vol II, pp 621–675
Puvion E, Lange M (1980) Functional significance of perichromatin granule accumulation induced by cadmium chloride in isolated rat liver cells. Exp Cell Res 128:47–58
Puvion E, Bachellerie J-P, Burglen M-J (1979) Nucleolar perichromatin granules induced by dichlorobenzimidazole riboside. J Ultrastruct Res 69:1–12
Puvion E, Puvion-Dutilleul F, Leduc EH (1981) The formation of nucleolar perichromatin granules. U Ultrastruct Res 76:181–190
Setoguti T, Satou Y, Goto Y (1979) Specific lamellar structures in the senile mouse adrenal cortex. Arch Histol Jpn 42:95–102
Tasso F, Rua S (1978) Ultrastructural observations on the hypothalamo-posthypophysial complex of the Brattleboro rat. Cell Tissue Res 191:267–286
Usdin E, Kvetnansky R, Kopin IJ (eds) (1975) Catecholamines and stress. Pergamon Press, Oxford
Watson ML (1962) Observations on a granule associated with chromatin in the nuclei of cells of rat and mouse. J Cell Biol 13:162–167
Weinshilboum RM, Kvetnansky R, Axelrod J, Kopin IJ (1971) Elevation of serum dopamine-β-hydroxylase activity with forced immobilization. Nature 230:287–288
Author information
Authors and Affiliations
Additional information
Supported by DFG, grants He 919/5 and Ad 54/2
Rights and permissions
About this article
Cite this article
Heym, C., Addicks, K. Formation of perichromatin granules, nematosomes and concentric lamellar bodies in sympathetic postganglionic perikarya in response to immobilization stress. Anat Embryol 165, 281–290 (1982). https://doi.org/10.1007/BF00305482
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00305482