Summary
Embryonic development of the mammalian eye has not been studied in such great detail as that of the avian eye, and preliminary observations have suggested that the sequence of events may differ. It is therefore likely that the relative importance of the cell and tissue interactions involved also differs and it would be interesting to compare these two systems.
The pupoid foetus mutation in the mouse shows disruption of eye development due to abnormal epidermal properties and so the relative importance of individual events in triggering subsequent development can be studied by seeing what happens when the situation is modified in the mutant.
The behaviour of the pupoid foetus epidermal cells in the interactive system of the eye may also help to further characterise the phenotype of the mutation.
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References
Anderson S (1984) Developmental abnormalities of the eye and snout region of the pupoid foetus mouse mutant. Ph. D. thesis, University of Glasgow
Anderson S, Ede DA (1985), The behaviour in vitro of epidermal cells from normal and pupoid foetus mutant mouse embryos. J Cell Sci 79:305–315
Anderson S, Ede DA, Watson PJ (1985) Embryonic development of the mouse mutant pupoid foetus (pf/pf) Anat Embryol 172:115–122
Cintron C, Covington H, Kublin CL (1983) Morphogenesis of rabbit corneal stroma. Invest Ophthalmol Vis Sci 24:543–556
Coulombre AJ, Coulombre JL (1961) The development of structural and optical properties of the cornea. In: Smelser G (ed) Structure of the Eye. Academic Press, New York, pp 405–420
Fisher C, Dale BA, Kollar EJ (1984) Abnormal keratinization in the pupoid foetus (pf/pf) mutant mouse epidermis. Dev Biol 102:290–299
Fisher C, Kollar EJ (1985) Abnormal skin development, in pupoid foetus (pf/pf) mutant mice. J Embryol Exp Morphol 87:47–64
Fraser-Rowell CH (1963) A general method for silvering invertebrate nervous systems. Q J Micr Sci 104:81–87
Green MC (ed) (1981) Genetic variants and strains of the laboratory mouse. Gustav Fischer, Stuttgart, New York
Guenet JL, Salzgeber B, Tassin MT (1979) Repeated epilation: a genetic epidermal syndrome in mice. J Hered 70:90–94
Harris MJ, Juriloff DM (1986) Eyelid development and fusion induced by cortisone treatment in mutant, lidgap-Miller, foetal mice. A scanning electron microscope study. J. Embryol Exp Morphol 91: 1–18
Hay ED (1980) Development of the vertebrate cornea. Int Rev Cytol 63:263–322
Hay ED (1982) Cell-matrix interactions in the embryonic avian cornea and lens. In: Extracellular matrix. Academic Press, New York, p 55
Hay ED, Revel JP (1969) Fine structure of the developing avian cornea. In: Wolsky Chen (ed) Monographs in Developmental Biology. Karger, Basel, vol 1, pp 1–144
Holbrook KA, Dale BA, Brown KS (1982), Abnormal epidermal keratinization in the repeated epilation mutant mouse. J Cell Biol 92:287–397
Meier S, Hay ED (1973) The synthesis of sulphated glycosamino-glycans by embryonic corneal epithelium. Dev Biol 35:318–322
Meyer DB, O'Rahilly R (1959) The development of the cornea in the chick. J Embryol Exp Morphol 7:303–315
Newgreen DF, Thiery J-P (1980) Fibronectin in early avian embryos: synthesis and distribution along the migration pathways of neural crest cells. Cell Tissue Res 211:269–291
Newgreen DF, Gibbins I, Sauter J, Wallenfels B, Watz R (1982) Ultrastructural and tissue culture studies on the role of fibronectin, collagen and glycosaminoglycans in the migration of neural crest cells in the fowl embryo. Cell Tissue Res 221:521–549
Pei YF, Rhodin JAG (1970) Prenatal development of the mouse eye. Anat Rec 168:105–126
Rugh R (1968) The Mouse: its reproduction and development. Burgess Publishing Co, Minneapolis
Tassin MT, Salzgeber B, Guenet JL (1983) Studies on “repeated epilation” mouse mutant embryos: 1 Development of facial malformations. J Craniofac Genet Dev Biol 3:289–307
Trelstad RC, Hayashi K, Toole BP (1974) Epithelial collagens and glycosaminoglycans in the embryonic cornea. J Cell Biol 62:815–830
Watson PJ (1978) Inherited developmental abnormalities in the pupoid foetus mutant mouse. Ph.D. thesis, University of Glasgow
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Anderson, S., Ede, D.A. Eye development in the normal and Pupoid foetus (pf/pf) mutant mouse. Anat Embryol 176, 243–249 (1987). https://doi.org/10.1007/BF00310058
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DOI: https://doi.org/10.1007/BF00310058