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Pituitary abnormalities detected by high resolution computed tomography with thin slices in primary hypothyroidism and Turner syndrome

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Abstract

Pituitary hyperplasia, microadenoma or an empty sella was detected in three children with primary hypothyroidism and three with Turner syndrome with the use of high resolution contrast-enhanced computed tomography (CT) with thin slices. Hyperplasia or microadenoma of the pituitary gland frequently occurs secondary to primary hypothyroidism and gonadal dysgenesis, and recognition of these results may eliminate unnecessary surgery in favor of hormone replacement therapy. High resolution contrast-enhanced CT, especially coronal CT, with thin slices is very helpful in demonstrating these pituitary abnormalities.

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References

  1. Danziger J, Wallace S, Handle S, Samaan NB (1979) The sella turcica in primary end organ failure. Neuroradiology 131:111–115

    Google Scholar 

  2. Di Chiro G, Nelson KB (1962) The volume of the sella turcica. Am J Roentgenol 87:989–1008

    Google Scholar 

  3. Furth J, Dent JN, Burnett WT, Gadsden EL (1955) The mechanism of induction and the characteristics of pituitary tumors induced by thyroidectomy. J Clin Endocrinol Metab 15:81–97

    Google Scholar 

  4. Gup RS, Sheeler LR, Maeder MC, Tew JM (1982) Pituitary enlargement and primary hypothyroidism: a report of two cases with sharply contrasting outcomes. Neurosurgery 11:792–794

    Google Scholar 

  5. Haughton VM, Rosenbaum AE, Williams AL, Drayer B (1981) Recognizing the empty sella by CT: The infundibulum sign. Am J Roentgenol 136:293–295

    Google Scholar 

  6. Houssay BA, Houssay AB, Cardez AF (1955) Estrogenic adrenal gland tumours and pituitary tumours in castrated animals. Schweiz Med Wochenschr 85:291–297

    Google Scholar 

  7. Okuno T, Sudo M, Momoi T, Takao T, Ito M, Konishi Y, Yoshida M, Suzuki J, Nakano Y (1980) Pituitary hyperplasia due to hypothyroidism. J Comput Assist Tomogr 4:600–602

    Google Scholar 

  8. Samaan NA, Osborne BM, Mackay B, Leavens ME, Duello TM, Halmi NS (1977) Endocrine and morphologic studies of pituitary adenomas secondary to primary hypothyroidism. J Clin Endocrinol Metab 45:903–911

    Google Scholar 

  9. Samaan NA, Stepanas AV, Danziger J, Trujillo J (1979) Reactive pituitary abnormalities in patients with Klinefelter's and Turner's syndromes. Arch Intern Med 139:198–201

    Google Scholar 

  10. Stockigt JR, Essex WB, West RH, Murray RML, Breidahl HD (1976) Visual failure during replacement therapy in primary hypothyroidism with pituitary enlargement. J Clin Endocrinol Metab 43:1094–1100

    Google Scholar 

  11. Swischuk LE, Sarwar M (1977) The sella in childhood hypothyroidism. Pediatr Radiol 6:1–3

    Google Scholar 

  12. Syversten A, Haughton VM, Williams AL, Cusick JF (1979) The computed tomographic appearance of the normal pituitary gland and pituitary microadenoma. Radiology 133:385–391

    Google Scholar 

  13. Uozumi T, Sakoda K, Ohta M, Iguchi T, Mori S (1983) The image diagnosis of the pituitary adenomas. In: Shizume K, Imura H, Shimizu N (eds) Proceeding of the seventh Asia and Oceania congress of endocrinology. Excerpta Medica, Amsterdam, pp 469–473

    Google Scholar 

  14. Wilkinson IA, Duck SC, Gager WE, Daniels DL (1982) Emptysella syndrome. Am J Dis Child 136:245–247

    Google Scholar 

  15. Yamada T, Tsukui T, Ikejiri K, Yukimura Y, Kotani M (1976) Volume of sella turcica in normal subjects and in patients with primary hypothyroidism and hyperthyroidism. J Clin Endocrinol Metab 42:817–822

    Google Scholar 

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Nishi, Y., Sakano, T., Hyodo, S. et al. Pituitary abnormalities detected by high resolution computed tomography with thin slices in primary hypothyroidism and Turner syndrome. Eur J Pediatr 142, 25–28 (1984). https://doi.org/10.1007/BF00442585

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  • DOI: https://doi.org/10.1007/BF00442585

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