Abstract
Plasma fibronectin (FN) concentrations were measured by an immunonephelometric method in cord blood from 76 healthy newborns (45 full term and 31 preterm), in 181 healthy children, from 1 month–15 years old, divided by age into seven groups and in 81 control adults. FN levels in newborns were 35% of those of adults. There was no difference between plasma FN in term and preterm (gestational age>30 weeks) infants. Preterm newborns below the gestational age of 30 weeks showed particularly low FN levels. No clear correlation was seen with birth weight. In the child population, a strong increase in FN values was noted in the first 6 months of life, rising to 65% of the normal adult values. No further increase occurred until puberty.
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Abbreviations
- FN:
-
fibronectin
- RES:
-
reticuloendothelial system
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Valletta, E.A., Bonazzi, L., Zuanazzi, R. et al. Plasma fibronectin concentrations in healthy newborns and in children. Eur J Pediatr 147, 68–70 (1988). https://doi.org/10.1007/BF00442615
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DOI: https://doi.org/10.1007/BF00442615