Abstract
We report a rare case of primary hyperaldosteronism in an 11-year-old female patient due to a unilateral adrenal cortical adenoma. The patient presented with hypertension, hypokalaemia and metabolic alkalosis associated with inappropriate kaliuresis. The diagnosis was supported by the following laboratory findings: elevated plasma aldosterone, suppressed plasma renin activity, nonsuppressible aldosterone secretion following saline infusion and absent plasma aldosterone response to ambulation. MRI revealed a 1 cm diameter adrenal tumour on the left side. Even though the NP-59 scintigraphy gave a negative result, laparotomy with left adrenalectomy was performed. Pathological examination confirmed an adenoma in the adrenal cortex. The patient's blood pressure and biochemical laboratory data normalized postoperatively within 2 days. We recommend that in hypertensive children with hypokalaemia and metabolic alkalosis, primary aldosteronism should be considered.
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Abbreviations
- APA :
-
aldosterone-producing adenoma
- PAC :
-
plasma aldosterone concentration
References
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Li, J.T., Shu, S.G. & Chi, C.S. Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature. Eur J Pediatr 153, 480–482 (1994). https://doi.org/10.1007/BF01957000
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DOI: https://doi.org/10.1007/BF01957000