Summary
Combined treatment with DMBA, 6-methylprednisolone, and 30% saline solution induced papillomas in the forestomach of mice after a median latent period of 25 days.
References
Blum AL, Siewert JR (1978) Ulcus-Therapie. Springer, Berlin Heidelberg New York
Dodi G, Farini R, Pedrazzoli S, Zannini G, Naccarato R, Lise M, Fagiolo U (1978) Effect of cimetidine on steroid experimental peptic ulcers. Acta Hepato-Gastroenterol 25:395–397
Gibson GG, Joannides C (eds) (1981) Safety evaluation of nitrosatable drugs and chemicals Taylor and Francis, London
Görttler K, Löhrke H, Schweizer J, Hesse B (1979) Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phrobol ester 12-O-tetradecanoylphorbol-13-acetate as promotor. Cancer Res 39:1293–1297
Habs M, Habs H (1981) Durchführung und Auswertung von Tierversuchen zur Cancerogenese. In: Schmähl D (ed) Maligne Tumoren-Enstehung, Wachstum, Chemotherapie. Edition Cantor, Aulendorf, pp 42–49
Schmähl D (ed) (1981) Maligne Tumoren-Entstehung Wachstum, Chemotherapie, Editio Cantor, Aulendorf
Schmähl D, Thomas C, Auer R (1977) Iatrogenic carcinogenesis. Springer, Berlin Heidelberg New York
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Wagner, G., Habs, M. & Schmähl, D. Influence of daily subcutaneous administration of 6-methylprednisolone and oral application of 30% saline solution on tumorigenesis induced in mouse stomach by single application of 7,12-dimethylbenz(a)anthracene. J Cancer Res Clin Oncol 103, 207–209 (1982). https://doi.org/10.1007/BF00409650
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DOI: https://doi.org/10.1007/BF00409650